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Organo Oficial de la Sociedad Mexicana de Urología

2019, Number 3

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Rev Mex Urol 2019; 79 (3)

Clinical characteristics and functional and oncologic results of patients with kidney tumors that underwent partial nephrectomy

Herrera MJA, Preciado EDA, Villalpando GL, Santana RZ, Martínez CP, Scavuzzo A, Jiménez RMÁ

Language: English
References: 35
Page: 1-12
PDF size: 243.73 Kb.


ABSTRACT

Background: Partial nephrectomy has become standard treatment for T1 tumors (≤ 7 cm), solitary kidney, bilateral tumors, and hereditary cancer. There are few studies in Mexico that report on said procedure.
Aim: To know the clinical characteristics, perioperative morbidity, and functional and oncologic results of partial nephrectomy at the Instituto Nacional De Cancerología
Materials and methods: A retrospective, analytic study was conducted on patients that underwent partial nephrectomy within the time frame of 2000 to 2018, reporting the oncologic and perioperative results.
Results: Seventy-nine patients that underwent partial nephrectomy were analyzed. A total of 82 procedures were performed. Mean patient age was 52 years. Clinical stage was T1a and T1b in 62 (74.6%) and 20 (24.4%) cases, respectively. Warm ischemia was utilized in 39 (47.6%) patients and n ischemia was used in 35 (42.7%). Mean surgery duration was 162 min, mean blood loss was 449 ml, and mean hospital stay was 2.1 days. Open surgery was performed on 70 (85.4%) patients and 12 (14.6%) patients underwent the laparoscopic procedure. There were early complications in 17 (20%) patients that included 9 (11%) transfusions. Clear cell renal cell carcinoma was reported in 66 (80.5%) cases and surgical margins were negative in 73 (89%). Cancer-specific survival was 100% and overall survival was 92% at five years. The mean preoperative estimated glomerular filtration rate was 88 ml/min and it was 79 ml/min at one year. Renal ischemia influenced the decrease in the glomerular filtration rate.
Conclusions: The results of the present study are similar to those reported in other international referral centers, making the performance of partial nephrectomy in T1 tumors a safe procedure in our population.


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