Ramos RC, Bello LPH, Sosa AN

Language: Spanish
References: 14
Page: 58-64
PDF size: 265.45 Kb.

ABSTRACT

Introduction: Childhood glaucoma is a disease associated with significant loss of vision. It is responsible for 5% blindness in children throughout the world. Optical coherence tomography (OCT) images are used in the diagnosis and monitoring of children with visual impairment. There is little evidence in the literature of parameters in the Mexican pediatric population. Objective: To evaluate the thickness of retinal nerve fiber layer (RNFL), disc area and thickness of ganglion cell layer (GCL) by means of OCT in Mexican pediatric population. Material and methods: The parents of the children who were selected were invited to sign the consent, visual acuity, macular OCT and optic nerve were taken. The thickness of GCL, thickness of RNFL and disk area were evaluated. Results: Total 76 eyes of 38 individuals, 17 females, 21 males, age from 3 to 17 years. The thickness of RNFL: average of 101.11 ± 15.03 µm, area of disk 2.23 ± 0.34 µm, average of average CCG of 84.8 ± 6.86 µm. Discussion: Average numbers of CFNR, disc area and GCL were found similar to the literature, although with certain minimum differences suggestive of ethnic changes. Conclusions: The usefulness of OCT in the evaluation and monitoring of pediatric patients to establish early diagnoses.

REFERENCES

1. Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014; 121 (11): 2081-2090.

2. Al-Haddad C, Barikian A, Jaroudi M, Massoud V, Tamim H, Noureddin B. Spectral domain optical coherence tomography in children: normative data and biometric correlations. BMC Ophthalmol. 2014; 14: 53.

3. Samarawickrama C, Wang JJ, Huynh SC et al. Ethnic differences in optic nerve head and retinal nerve fiber layer thickness parameters in children. Br J Ophthalmol. 2010; 94 (7): 871-876.

4. Pawar N, Maheshwari D, Ravindran M, Ramakrishnan R. Retinal nerve fiber layer thickness in normal Indian pediatric population measured with optical coherence tomography. Indian J Ophthalmol. 2014; 62 (4): 412-418.

5. Quiñóez Quiñónez W et al. Espesor de la capa de fibras nerviosas y células ganglionares de la retina mediante tomografia de coherencia óptica en una población mexicana sana menor de 18 años. Rev Mex Oftalmol. 2016.

6. Hoguet A, Grajewski A, Hodapp E, Chang TC. A retrospective survey of childhood glaucoma prevalence according to Childhood Glaucoma Research Network classification. Indian J Ophthalmol. 2016; 64 (2): 118-123.

7. El-Dairi MA, Asrani SG, Enyedi LB, Freedman SF. Optical coherence tomography in the eyes of normal children. Arch Ophthalmol. 2009; 127 (1): 50-58.

8. Yanni SE, Wang J, Cheng CS, Locke KI, Wen Y, Birch DG et al. Normative reference ranges for the retinal nerve fiber layer, macula, and retinal layer thicknesses in children. Am J Ophthalmol. 2013; 155 (2): 354-360.

9. Griñó García-Pardo C, Lugo-Quintás F, León M, Ligero S, Ruiz-Moreno JM, Montero-Moreno J. Tomografía de Coherencia Óptica (OCT). Funcionamiento y utilidad en patología macular (III). Gaceta Óptica. 2012; 427: 12-14.

10. Yanoff M, Ducker JS. Optic nerve analysis. 4th edition. Elsevier; 2014. p. 1040.

11. Alasil T, Keane PA, Sim DA, Tufail A, Rauser ME. Optical coherence tomography in pediatric ophthalmology: current roles and future directions. Ophthalmic Surg Lasers Imaging Retina. 2013; 44 (6 Suppl): S19-S29.

12. Leung MM, Huang R, Lam A. Retinal nerve fiber layer thickness in normal Hong Kong Chinese children measured with optical coherence tomography. J Glaucoma. 2010; 19: 95-99.

13. Totan Y, Gürağaç FB, Güler E Evaluation of the retinal ganglion cell layer thickness in healthy Turkish children. J Glaucoma. 2015; 24 (5): e103-e108.

14. Qian J, Wang W, Zhang X, Wang F, Jiang Y, Wang W et al. J Optical coherence tomography measurements of retinal nerve fiber layer thickness in chinese children and teenagers. Glaucoma. 2011; 20 (8): 509-513.