2019, Number S1
<< Back Next >>
Cir Cir 2019; 87 (S1)
Hyperparathyroidism during pregnancy. Is it a diagnostic and therapeutic challenge?
Godínez-Vidal AR, Montes de Oca-Durán É, Aguirre-Rojano VI, Pulido-Cejudo A, Paul-Basurto-Kuba EO, Hurtado-López LM
Language: Spanish
References: 22
Page: 62-67
PDF size: 314.49 Kb.
ABSTRACT
Background: Primary hyperparathyroidism (PHPT) is characterized by an increase in parathyroid hormone (PTH) and hypercalcemia,
which, when present during pregnancy, increases both maternal and fetal morbidity and mortality.
Objective: Emphasize
the importance of surgical intervention in primary hyperparathyroidism during pregnancy.
Clinical case: A 27-year-old
female with a pregnancy of 27.2 weeks of gestation, with a diagnosis of symptomatic primary hyperparathyroidism secondary
to parathyroid adenoma, a history of nephrolithiasis and severe acute pancreatitis, surgery was decided upon finding intrathyroid
right parathyroid adenoma, post-surgical course with adequate evolution and remission of hyperparathyroidism.
Conclusions: Parathyroidectomy in primary hyperparathyroidism during pregnancy is safe.
REFERENCES
Marx SJ. Hyperparathyroid and hypoparathyroid disorders. N Engl J Med. 2000;343:1863-75.
Herrera-Martínez AD, Bahamondes-Opazo R, Ortega Palomares, Muñón-Jiménez C, Gálvez-Moreno MA, Quesada Gómez JM. Primary hyperparathyroidism in pregnancy: a two-case report and literature review. Case Rep Obstet Gynecol. 2015;2015:171828. Epub 2015 Mar 29
Hirsch D, Kopel V, Nadler V, Levy S, Toledano Y, Tsvetov G. Pregnancy outcomes in women with primary hyperparathyroidism. J Clin Endocrinol Metab, May 2015, 100(5): 2115-2122.
McMullen TP, Learoyd DL, Williams DC. Hyperparathyroidism in pregnancy: options for localization and surgical therapy. World J Surg. 2010; 34:1811–16.
Ammann P, Irion O, Gust J. Alterations of calcium and phosphate metabolism in primary hyperparathyroidism during pregnancy. Acta Obstet Gynecol Scand. 1993;72:488-92.
Kohlmeier L, Marcus R. Calcium disordes of pregnancy. Endocrinol Metab Clin North Am. 1995;24:15-39.
Carella MJ, Gossain VV. Hyperparathyroidism and pregnancy. Case report and review. J Gen Intern Med. 1992;7:448-53.
Hunter D, Turnbull H. Hyperparathyroidism: generalised osteitis fibrosa with observation upon bones, parathyroid tumor and the normal parathyroid gland. Br J Surg. 1931;19:203-6.
Eigelberger MS, Clark OH. Surgical approaches to primary hyperparathyroidism. Endocrinol Metab Clin North Am. 1995;29:479-502.
Schnatz PF, Curry SL. Primary hyperparathyroidism in pregnancy: evidence- based management. Obstet Gynecol Surv. 2002; 57:365-76.
Pachydakis A, Koutroumanis P, Geyushi B, Hanna L. Primary hyperparathyroidism in pregnancy presenting as intractable hyperemesis complicating psychogenic anorexia: a case report. J Reprod Med. 2008; 53:714.
Truong MT, Lalakea ML, Robbins P, Friduss M. Primary hyperparathyroidism in pregnancy: a case series and review. Laryngoscope. 2008; 118:1966.
Kort KC, Schiller HJ, Numann PJ. Hyperparathyroidism and pregnancy. Am J Surg. 1999;177:66.
Chamarthi B, Greene MF, Dluhy RG. Clinical problem-solving. A problem in gestation. N Engl J Med. 2011; 365:843.
Kovacs CS, Fulethan G. Calcium and bone disorders during pregnancy and lactation. Endocrinol Metab Clin North Am. 2006;35:21-9.
Kelly TR. Primary hyperparathyroidism during pregnancy. Surgery. 1991; 110:1028-34.
Davison K, Hawkins DS, Rubin LP. Serum parathyroid hormone in pregnant women determined by an inmunoradiometric assay for intact PTH. J Clin Endocrinol Metab. 1998;67:850-2.
Kovacs C, Kronenberg H. Maternal-fetal calcium and bone metabolism during pregnancy, puerperium and lactation. Endocr Rev. 1997;18:837-72.
Schnatz PF, Thaxton S. Parathyroidectomy in the third trimester of pregnancy. Obstet Gynecol Surv. 2005; 60 672.
Eller-Vainicher C, Chiodini I, Battista C, Viti R, Mascia ML, Massironi S, et al. Sporadic and MEN1-related primary hyperparathyroidism: differences in clinical expression and severity. J Bone Miner Res. 2009;24:1404-10.
Callender GG, Rich TA, Perrier ND. Multiple endocrine neoplasia syndromes. Surg Clin North Am. 2008;88:863–895.
Rajala MM, Heath H III. Distribution of serum calcium values in patients with familial benign hypercalcemia (hypocalciuric hypercalcemia): evidence for a discrete genetic defect. J Clin Endocrinol Metab. 1987; 65:1039–1041