2019, Number 3
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Acta Med 2019; 17 (3)
Procalcitonin as a predictor of reintervention in post-operative abdominal surgery patients
Arredondo OMA, Hernández AJF, Cortés RJJP
Language: Spanish
References: 17
Page: 225-229
PDF size: 167.85 Kb.
ABSTRACT
Objective: To determine whether serum procalcitonin levels in patients with abdominal surgery predict the need for surgical reintervention.
Material and methods: Retrospective analysis of serum procalcitonin levels in 46 patients admitted to an intensive care unit after abdominal surgery within a one-year period, and its association with the need of surgical reintervention.
Results: Serum procalcitonin values were significantly more elevated in patients who required surgical reintervention, compared to patients who did not required reintervention (9.46 ± 9.25 ng/mL vs 2.96 ± 3.93 ng/mL (p ≤ 0.05, CI
95%), respectively). Serum PCT ≥ 1.19 ng/mL resulted as the value with a higher sensibility (84.2%) and fair specificity (55.6%) in predicting the need for surgical reintervention, with an area under the curve of 0.75. Patients who were subject to colorectal surgery with PCT levels equal or higher to this cut-off point had a significantly higher risk of surgical reintervention.
Conclusion: Serum PCT levels could help recognize the need for surgical reintervention in patients submitted to abdominal surgery, with a higher sensibility in patients with colorectal surgery, although it should be clinically individualized to each patient due to the low specificity of this test in this particular context.
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