2019, Number 3
<< Back
Rev Clin Esc Med 2019; 9 (3)
Síndrome de Brugada
Monge OJM, Quesada ACI
Language: Spanish
References: 8
Page: 53-55
PDF size: 373.99 Kb.
ABSTRACT
Brugada Syndrome is an inherited condition
whose diagnosis is based on a electrocardiographic
pattern, which is associated with a risk of ventricular
fibrillation and sudden death. The literature
mentions that the causal mechanism may be
related to an abnormal repolarization of the right
ventricle related to sodium channel dysfunction.
The latest evidence points to an important genetic
role in up to a third of patients. The treatment is
complex especially in asymptomatic patients, but
the trend is the use of an implantable defibrillator.
The following is an electrocardiographic case of
Sindrome de Brugada, from which its characteristic
pattern and clinical importance will be described.
REFERENCES
Brugada J Campuzano O Arbelo E Sarquella- Brugada G Brugada R. Present status of Brugada Syndrome. JACC. 2018;9:1046-1059.
Probst V Wilde AA Barc J et al. SCN5A mutations and therole of genetic background in the pathophysiology of Brugada Syndrome. Circ Cardiovasc Genet 2009;2:552-557.
Brugada R Campuzano O Sarquella Brugada G et al. Brugada syndrome. Methodist Debakey Cardiovasc J. 2014;10(1):25–28.
Probst V Veltmann C Eckardt L et al. Long-term prog-nosis of patients diagnosed with Brugada syndrome: resultsfrom the FINGER Brugada Syndrome Registry. Circulation. 2010;121:635-643.
Arnalsteen-Dassonvalle E Hermida JS Kubala M et al. Ajma-line challenge for the diagnosis of Brugada syndrome: which protocol? Arch Cardiovasc Dis. 2010;103:570-578.
Batchvarov VN Govindan M Camm AJ Behr ER. Significance of QRS prolongation during diagnostic ajmaline testing patients with suspected Brugada syndrome. Heart Rhythm. 2009;6:625-631.
Nagase S Hiramatsu S Morita H et al. Electroanatomical correlation of repolarization abnormalities in Brugada syndrome: detection of type 1 electrocardiogram in the right ventricular outflow tract. J Am Coll Cardiol. 2010; 56:2143–2145.
Gourraud J Barc J Thollet A Marec H Probst V. Brugada syndrome: Diagnosis, risk stratification and management. Archive of Cardiovascular Disease. 2017; 110: 188-195.