2019, Number 4
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Gac Med Mex 2019; 155 (4)
De vuelta a la clínica. Métodos I. Diseños de investigación. Mayor calidad de información, mayor certeza a la respuesta
Talavera JO, Roy-García I, Palacios-Cruz L, Rivas-Ruiz R, Hoyo I, Pérez-Rodríguez M
Language: Spanish
References: 32
Page: 399-405
PDF size: 150.93 Kb.
ABSTRACT
Research designs refer to the way information is obtained and are limited by ethical, economic and temporal viability. Research
designs are standardized strategies to reduce biases, which in the architectural model of research are identified in the baseline
state, the maneuver and the outcome; hence, there are no specific designs for each question. The design with the lowest
probability of bias is the clinical trial, followed by cohort and case-control studies and, finally, by cross-sectional surveys. Among
the main characteristics that give merit to research designs are the following: population inquiry, which refers to the situation
of the population in relation to the clinical course/natural history of the disease; the maneuver, or action that is expected
to modify the baseline state, which can be observational or experimental; follow-up, or documented monitoring that is given to
each subject, which can be longitudinal or cross-sectional; and directionality, which can prolective or retrolective and refers to
the timing of data collection for research purposes. It will always be better having a valuable question, even when answered
with a design with higher risk of bias, than a question that is irrelevant or has no applicability.
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