2018, Number 2
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Cuba y Salud 2018; 13 (2)
Cutaneous leishmaniasis, herpes zoster and adverse effects of meglumine antimonate in Arizona Atlántida Honduras
Turcios MEN, Ortiz DCR
Language: Spanish
References: 21
Page: 126-130
PDF size: 740.10 Kb.
ABSTRACT
Leishmaniasis is a zoonosis with worldwide distribution, endemic in Central and South America included in neglected diseases. It
is caused by protozoa of the genus Leishmaniatransmitted to humans through the bite of sandfly insects of the genus Lutzomyia.
The evolution of the disease depends on the immune response and the species of the parasite. Cutaneous leishmaniasis is
the most frequent clinical form, mainly affecting exposed areas of the skin. Its usual clinical presentation is an ulcer with
slightly elevated edges, indurated, not painful and covered by serous or seropurulent secretion. It is easily diagnosed in endemic
areas, but its unusual forms are difficult to diagnose and can lead to inadequate treatment. Meglumine antimoniate is the
medication of first choice, however it is characterized by adverse effects and serious toxic reactions, as well as the reactivation of
varicella zoster virus. This article describes the case of a patient with cutaneous leishmaniasis and herpes zoster simultaneously,
without association with meglumine antimoniate, who presented moderate adverse effects during the twenty days of treatment.
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