2019, Number 03
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MediSan 2019; 23 (03)
Children and adolescents survival with acute lymphoblastic leukemia
Fernández VM, Pérez MY, Urgellés DD, Fernández VM
Language: Spanish
References: 12
Page: 412-423
PDF size: 1047.49 Kb.
ABSTRACT
A descriptive and retrospective study of 65 patients under 19 years assisted in the
Hematology Service of Dr. Antonio María Béguez Caesar Teaching Southern Pediatric
Hospital in Santiago de Cuba was carried out in the period 2001-2005, but with
continued follow-up to December, 2015, with the objective of describing some
parameters related to the survival of this populational group, for which some variables
of interest for the individual medical records were analyzed. The age group 1-4 years
(43.1 %), male sex (55.4 %), morphological variant L1 (96.9 %) and early relapses
prevailed in the series. In general, the high survival was related to the use of modern
treatments and comprehensive protocols; while the deaths took place mostly due to
relapses and during the induction phase.
REFERENCES
Linet MS, Brown LM, Mbulaiteye SM, Check D, Ostroumova E, Landgren A et al. International long-term trends and recent patterns in the incidence of leukemias and lymphomas among children and adolescents ages 0-19 years. Int J Cancer. 2016;138:1862-74.
Jiménez Hernández E, Dueñas González MT, Arellano Galindo J, Medrano Ortiz De Zárate ME, Bekker Méndez VC, Berges García A. Survival of Mexican children with acute myeloid leukaemia who received early intensification chemotherapy and an autologous transplant. Biomed Res Int. 2015; 2015: 940278.
Marsán Suárez V, Sánchez Segura M, Socarrás Ferrer BB, Martínez Machado M, Cos Padrón Y, Valle Pérez L del, et al. Leucemia linfoide aguda común. Estudio del inmunofenotipo y las características clínicas y morfológicas. Rev Cubana Hematol Inmunol Hemoter. 2004 [citado 13/07/2018];20(2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-02892004000200006
Jiménez Hernández E, Jaimes Reyes EZ, Arellano Galindo J, García Jiménez X, Tiznado García HM, Dueñas González MT. Survival of Mexican children with acute lymphoblastic leukaemia under treatment with the protocol from the Dana-Farber Cancer Institute 00-01. Biomed Res Int. 2015; 2015:576950.
Puumala SE, Ross JA, Aplenc R, Spector LG. Epidemiology of childhoodacute myeloid leukemia. Pediatr Blood Cancer. 2013; 60(5):728-33.
Rivera Luna R, Shalkow Klincovstein J, Velasco Hidalgo L, Cárdenas Cardós R, Zapata Tarrés M, Olaya Vargas A, et al. Descriptive epidemiology in Mexican children with cancer under an open national public health insurance program. BMC Cancer. 2014; 14:790,
Cuba. Ministerio de Salud Pública. Dirección de Registros Médicos y Estadísticas de Salud. Anuario estadístico de salud. 2015. La Habana: MINSAP; 2016 [citado 13/07/2018]. Disponible en: http://files.sld.cu/dne/files/2016/04/Anuario_2015_electronico-1.pdf
Grove CS, Vassiliou GS. Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer? Dis Model Mech. 2014; 7(8):941-51.
Cancer Research UK. Acute myeloid leukaemia (AML) incidence statistics [citado 13/07/2018]. Disponible en: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/leukaemia-aml/incidence
Mejía Aranguré JM. Molecular epidemiology of acute leukemia in children: causal model, interaction of three factors-susceptibility, environmental exposure and vulnerability period. Bol Med Hosp Infant Mex. 2016;73(1):55-63.
Booth BJ, Ward MH, Turyk ME, Stayner LT. Agricultural crop density and risk of childhood cancer in the Midwestern United States: an ecologic study. Environ Health. 2015; 14:82.
Souza Melo CP, Campos CB, Dutra AP, Neto CG, Fenolon AJ, Neto AH, et al. Correlation between FLT3-ITD status and clinical, cellular and molecular profiles in promyelocytic acute leukemias. Leuk Res. 2015; 39(2):131-7.