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ISSN 1995-9494 (Electronic)
Revista del Hospital Clínico Quirúrgico "Arnaldo Milián Castro"

2019, Number 3

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Acta Med Cent 2019; 13 (3)

Actividad de la enzima mieloperoxidasa en trabajadores

González FA, Fanjul LNM, Jaime VL, Garcés GO, Álvarez AA, Pérez LI

Language: Spanish
References: 27
Page: 367-377
PDF size: 220.42 Kb.


ABSTRACT

Introduction: In the evolution of atherosclerotic cardiovascular disease, oxidative stress is proposed as a potential inducer of inflammation. One of the enzymes of oxidative stress, that links ischemia reperfusion diseases and inflammatory diseases, is myeloperoxidase. Objective: to determine the relationship between the activity of the enzyme myeloperoxidase and different variables such as sex, age and blood levels of glucose, cholesterol and triacylglycerides in workers at the Faculty of Medicine. Methods: A cross-sectional descriptive study was conducted at the Faculty of Medicine of the University of Medical Sciences in Villa Clara from January 2015 to December 2016. The population consisted of 416 workers and a sample of 90 people was selected by probabilistic sampling. The activity of the enzyme myeloperoxidase in serum was determinedin them, as well as blood levels of cholesterol, triglycerides and glucose. Results: The average value of the activity of this enzyme in men is 0.233 -higher than the value of 0.212 corresponding to women-, in relation to skin color the average values of enzyme activity were 0.227 for non-whites and 0.220 for whites and the average values of enzyme activity tend to increase as it approaches the values of 25 to 29.9kg/m2 and ≥30.00kg/m2 of body mass index. Conclusions: Myeloperoxidase activity is related to increased glycemia, overweight and male sex.


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