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Colegio de Medicina Interna de México.

2019, Number 2

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Med Int Mex 2019; 35 (2)

Predictive capacity of myoglobin vs total creatine kinase of acute renal failure in traumatized patients

Palacios-Pérez E, Cerda-Téllez F, Suárez-Cuenca J, Elizalde CI, García-Sánchez JL, Hernández-Sánchez M, Vergara-Orduña F

Language: Spanish
References: 40
Page: 191-197
PDF size: 234.54 Kb.


ABSTRACT

Objective: To compare the predictive capacity of myoglobin, total creatine kinase and urine hemoglobin for acute renal injury in patients with trauma.
Material and Method: A cross-sectional, analytical, comparative, observational study was made with all adults over 18 years of age with a diagnosis of trauma or polytraumatism from August 2017 to January 2018 in the General Hospital of Xoco, Mexico City. Myoglobin, total creatine kinase, creatinine and hemoglobin levels were measured in urine at their admission.
Results: There were studied 24 patients from 20 to 79 years old, with a predominance of the male gender. When comparing the areas under the test curve it was determined that there was no statistical significance (p = 0.266) for the creatine kinase at the patient’s admission, as it showed an area under the curve of 0.636, the 95% confidence interval was below 0.500. Likewise, the myoglobin at the patient’s admission was observed under the curve area of 0.657 (p = 0.198; IC 95% 0.423-0.891).
Conclusions: Levels of total creatine kinase and myoglobin did not prove to be adequate predictors of kidney injury because there was no significant difference. However, creatinine levels at admission have greater predictive capacity of acute renal injury in patients with trauma and hyperCKemia.


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