Giraldo-Ospina B, Garzón-Castaño SC, López-Muñoz DF, Cardozo-Rios L, Millán-Benavidez N

Language: Spanish
References: 0
Page: 356-361
PDF size: 163.60 Kb.

ABSTRACT

Objective: To determinate seroprevalence of Toxoplasma gondii in the female population of the municipality of Dosquebradas.
Materials and Methods: Cross-sectional prevalence study in reproductive age female of two school of the from a locality of Dosquebradas, Colombia, during 2016, was approved by the ethics committees of the participating institutions. The study volunteers signed the consent and completed the survey with demographic data, excluding women older than 18 years, and having had previous pregnancies. The samples were analyzed against IgM, IgG and avid IgG antibodies using highly purified recombinant antigens for Toxoplasma gondii using RecomLine test with development of Western blot mikrogen DIAGNOSTIK. To define the infectious moment, anti-IgG avidity against antigens p30, MAG1, GRA1 and rSAG1 were determined in samples positive for total IgG. The test was performed and interpreted according to the manufacturer’s instructions.
Results: 80 patients were studied with average age of 15 years, 4 presented IgM anti-Toxoplasma gondii, infection less than 3 months; 28 IgG anti-Toxoplasma gondii, with infection greater than 3 months and 17 IgG of avidity with infection greater than 6 months, representing a prevalence of 61.3%.
Conclusions: The global seroprevalence of anti-toxoplasma antibodies was 61.3%, which shows that toxoplasmosis is a disease in which it must be thought to diagnose and treat it in a timely manner.