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2019, Number 1

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AbanicoVet 2019; 9 (1)

Cassia fistula extract as alternative treatment against gastrointestinal nematodes of sheep

Zaragoza-Bastida A, Rodríguez-Salazar E, Valladares-Carranza B, Rivas-Jacobo M, Herrera-Corredor A, Rivero-Perez N

Language: Spanish
References: 20
Page: 1-10
PDF size: 270.21 Kb.


Text Extraction

Gastrointestinal nematodes are an important issue in sheep production, these nematodes have developed resistance to traditional drugs, so it is necessary to search new functional and economic therapeutic alternatives; such as the use of plant extracts that have anthelmintic activity, Cassia fistula is a Leguminosae, due to its content of phenolic compounds, that can exhibit this activity, the aim of the present experiment was to determine the anthelmintic activity of hydroalcoholic extract from pods of Cassia fistula (LO) in vitro, using field nematodes in egg and larval stages to determine the inhibition percentage of eggs hatching and larval mortality. A hydroalcoholic extract of Cassia fistula pods was elaborated, stool samples of 20 sheep were collected, the feces were subjected to a parasitoscopic analysis to determine the presence of nematodes and eggs per gram of feces, they were used to obtain eggs and larvae, once obtained, they were challenged with LO (50, 25, 12.5 and 6.26 mg / mL) after the incubation time had elapsed, the percentages of eggs hatching inhibition and larval mortality close to 30% were determined. This suggests that LO has anthelmintic potential on gastrointestinal nematodes of sheep.


REFERENCES

  1. ANTONISAMY, P., Agastian, P., Kang, C.-W., Kim, N. S., & Kim, J.-H. 2017. Anti-inflammatory activity of rhein isolated from the flowers of Cassia fistula L. and possible underlying mechanisms. Saudi Journal of Biological Sciences. 18. 129-133. doi:10.1016/j.sjbs.2017.04.011

  2. CALA AC, Chagas AC, Oliveira MC, Matos AP, Borges LM, Sousa LA, Souza FA, Oliveira GP. 2012. In vitro anthelmintic effect of Melia azedarach L. and Trichilia claussenii C. against sheep gastrointestinal nematodes. Experimental Parasitology. 130(2), 98-102. doi:10.1016/j.exppara.2011.12.011

  3. CARVALHO CO, Chagas ACS, Cotinguiba F, Furlan M, Brito LG, Chaves FCM, Stephan MP, Bizzo HR, Amarante AFT. 2012. The anthelmintic effect of plant extracts on Haemonchus contortus and Strongyloides venezuelensis. Veterinary Parasitology.183(3-4), 260-268. doi:10.1016/j.vetpar.2011.07.051

  4. DURAIPANDIYAN V, Ignacimuthu S, & Paulraj MG. 2011. Antifeedant and larvicidal activities of Rhein isolated from the flowers of Cassia fistula L. Saudi Journal of Biological Sciences. 18(2), 129-133. doi:10.1016/j.sjbs.2010.12.009

  5. EGUALE T, Tadesse D, & Giday M. 2011. In vitro anthelmintic activity of crude extracts of five medicinal plants against egg-hatching and larval development of Haemonchus contortus. Journal Ethnopharmacology. 137(1), 108-113. doi:10.1016/j.jep.2011.04.063

  6. HERNÁNDEZ-ALVARADO J, Zaragoza-Bastida A, López-Rodríguez G, Peláez-Acero A, Olmedo-Juárez A, & Rivero-Perez N. 2018. Actividad antibacteriana y sobre nematodos gastrointestinales de metabolitos secundarios vegetales: enfoque en Medicina Veterinaria. Abanico Veterinario. 8, 14-27. doi:10.21929/abavet2018.81.1

  7. IRSHAD M, Man S, & Rizvi MA. 2010. Assessment of anthelmintic activity of Cassia fistula L. Middle East Journal of Scientific Research. 5(5), 346-349. http://www.idosi.org/mejsr/mejsr5(5)/5.pdf

  8. KAMARAJ C, & Rahuman AA. 2011. Efficacy of anthelmintic properties of medicinal plant extracts against Haemonchus contortus. Research in Veterinary Science. 91(3), 400-404. doi:10.1016/j.rvsc.2010.09.018

  9. KATIKI LM, Chagas AC, Bizzo HR, Ferreira JF, & Amarante AF. 2011. Anthelmintic activity of Cymbopogon martinii, Cymbopogon schoenanthus and Mentha piperita essential oils evaluated in four different in vitro tests. Veterinary Parasitology . 183(1-2), 103-108. doi:10.1016/j.vetpar.2011.07.001

  10. KUMARASINGHA R., Preston S, Yeo T-C, Lim DSL, Tu C-L, Palombo EA, Shaw JM, Gasser RB & Boag PR. 2016. Anthelmintic activity of selected ethno-medicinal plant extracts on parasitic stages of Haemonchus contortus. Parasites & Vectors. 9(1), 187. doi:10.1186/s13071-016-1458-9

  11. PETER JW, & Chandrawathani P. 2005. Haemonchus contortus: parasite problem No. 1 from tropics - Polar Circle. Problems and prospects for control based on epidemiology. Tropical biomedicine. 22(2), 131-137. https://www.ncbi.nlm.nih.gov/pubmed/16883278

  12. RAJAGOPAL PL, Premaletha K, Kiron SS, & Sreejith KR. 2013. Phytochemical and pharmacological review on Cassia fistula linn. - "The Golden Shower". International Journal of Pharmaceutical, Chemical & Biological Sciences. 3(3), 672-679.

  13. RIOS-DE ALVAREZ L., Jackson F., Greer A., Bartley Y., Bartley D.J., Grant G., & Huntley J. F. 2012. In vitro screening of plant lectins and tropical plant extracts for anthelmintic properties. Veterinary Parasitology . 186(3-4), 390-398. doi:10.1016/j.vetpar.2011.11.004

  14. RIVERO-PEREZ N, Zaragoza-Bastida A, Vega-Sánchez V, Olave-Leyva I, Vega-Angeles J, & Peña-Jiménez F. 2018. Identificación de los principales parásitos gastrointestinales en burros del Valle de Tulancingo. Abanico Veterinario . 8, 47-52.

  15. ROEBER F, Jex AR & Gasser RB. 2013. Advances in the diagnosis of key gastrointestinal nematode infections of livestock, with an emphasis on small ruminants. Biotechnology Advances. 31(8), 1135-1152. doi:10.1016/j.biotechadv.2013.01.008

  16. SRIVIDHYA M, Hridya H, Shanthi V, & Ramanathan K. 2017. Bioactive Amento flavone isolated from Cassia fistula L. leaves exhibits therapeutic efficacy. 3 Biotech. 7(1), 33. doi:10.1007/s13205-017-0599-7

  17. VON SON-DE FERNEX E, Alonso-Díaz MA, Mendoza-de Gives P, Valles-de la Mora B, González-Cortazar M, Zamilpa A, & Castillo Gallegos E. 2015. Elucidation of Leucaena leucocephala anthelmintic-like phytochemicals and the ultrastructural damage generated to eggs of Cooperia spp. Veterinary Parasitology . 214(1), 89-95. doi:10.1016/j.vetpar.2015.10.005

  18. ZABRE G, Kabore A, Bayala B, Katiki LM, Costa-Junior LM, Tamboura HH, Belem GAM, Abdalla AL, Niderkorm V, Hoste H & Louvandini H. 2017. Comparison of the in vitro anthelmintic effects of Acacia nilotica and Acacia raddiana. Parasite. 24, 44. doi:10.1051/parasite/2017044

  19. ZAPATA SR, Velásquez VR, Herrera OLV, Ríos OL, & Polanco EDN. 2016. Prevalencia de Nematodos Gastrointestinales en Sistemas de Producción Ovina y Caprina bajo Confinamiento, Semiconfinamiento y Pastoreo en Municipios de Antioquia, Colombia. Revista de Investigaciones Veterinarias del Perú. 27(2), 344 - 354. doi:10.15381/rivep.v27i2.11647

  20. ZHAO W, Zeng X, Zhang T, Wang L, Yang G, Chen Y-K, Hu Q & Miao M. 2013. Flavonoids from the bark and stems of Cassia fistula and their anti-tobacco mosaic virus activities. Phytochemistry Letters. 6(2), 179-182. doi:10.1016/j.phyt ol.2012.12.006




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