2019, Number 1
Intra-thyroid granular cell tumor
Language: Spanish
References: 29
Page: 112-121
PDF size: 629.52 Kb.
ABSTRACT
Background: the granular cells tumors are uncommon benign lesions of slow growth that can appear in any place of the organism. The head and neck region includes the most frequent localizations (between the 30 and 50% of all the tumors of this type, including those of the central nervous system).Objective: to present a case of intra-thyroid granular cell tumor.
Clinical case: a case of a 37 year-old female patient with nodular illness of the thyroid of slow growth with scarce symptoms, with histologic confirmation of granular cells tumor is presented. To the physical exam, an increase of volume was identified in the anterolateral region of the neck, in connection with the right lobe of the thyroid gland that corresponded with a tumoral lesion of 3cm approximately, not well defined, stuck to deep planes, not painful to the palpation. In the echography, it was observed: right lobe of the thyroid of 4.3 cm x 1.2cm x 1.4 cm, not homogeneous with a nodular lesion of 2.8 x 1.4 cm not well defined, of irregular borders. During the surgery, a frozen section was examined and reported as positive of malignancy, however, the untimely histologic study revealed a benign intra-thyroid granular cell tumor. The surgical treatment is healing in this case.
Conclusions: the diagnosis of intra-thyroid benign granular cell tumor is presented with the characteristics of a malign tumor, it should be kept in mind in the differential diagnosis of the tumors of the thyroid.
REFERENCES
Eguia Del Valle A, Gay Escoda C, Crovetto de la Torre M, Martinez-Conde Llamosas R, Aguirre Urizar JM. Tumor de células granula-res: Presentación de 8 casos con localización intraoral. Med oral patol oral cir bucal [Internet]. 2006 Sep [citado 14 Dic 2018];11(5):[aprox. 4 p.]. Disponible en: http://scielo.isciii.es/scielo.php?script =sci_arttext&pid=S1698-69462006000500009
Estrada Sarmiento M, Acosta García J, Pizarro Ojea J, Virelles Espinosa I, Acosta Pantoja A, Ferrándiz Guerra S. Mioblastoma de células granulosas de la base de la lengua en el recién nacido. Rev Cubana Pediatr [Internet]. 2002 Sep [citado 13 Dic 2018];74(3):[aprox. 5 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75312002000300011&lng=es
Estrella V, Ortega V, Cabrini JM, Bergero A, Sarancone S, Fernández Bussy R. Tumor de células granulares: Reporte de un caso. Rev Argent Dermatol [Internet]. 2009 Jun [citado 13 Dic 2018];90(2):[aprox. 3 p.]. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-300X2009000200002&lng=es
Kintanar EB, Giordano TJ, Thompson NW, Michael CW. Granular-Cell Tumor of Trachea Masquerading as Hurthle-Cell. Neoplasm on Fine-Needle Aspirate: A Case Report. Diagn Cytopathol [Internet]. 2000 Jun [citado 14 Dic 2018];22(6):[aprox. 4 p.]. Disponible en: https://deepblue.lib.umich.edu/bitstream/handle/2027.42/ 35305/10_ftp.pdf?sequence=1&isAllowed=y
Lassaletta L, Alonso S, Granell J, Ballestín C, Serrano A, Álvarez-Vicent JJ. Synchronous Glottic Granular Cell Tumor and Subglottic Spindle Cell Carcinoma. Arch Oto-laryngol Head Neck Surg [Internet]. 1998 Sep [citado 14 Dic 2018];124(9):[aprox. 4 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/9738817
Peña González E, León Atance P, Peligro Gómez I, Moreno Mata N, González Aragone-ses F, Polqué Gómez E. Mioblastoma de célu-las granulosas localizado en la pared toráci-ca. Arch Bronconeumol [Internet]. 1998 [citado 13 Dic 2018];34(4):[aprox. 3 p.]. Disponible en: http://www.archbronconeumol.org/es/mioblastoma-celulas-granulosas-localizado-pared/articulo-resumen/S0300289615304567/.
Chen Q, Li Q, Guo L, Li S, Jiang Y. Fine needle aspiration cytology of a granular cell tumor arising in the thyroid gland: a case report and review of literature. Int J Clin Exp Pathol [Internet]. 2014 [citado 14 Dic 2018];7(8):[aprox. 6 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152085/.
Innocenti Castro FA, Klaassen Pinto R, Bravo Crisostomo F, Hinrichs Oyarce E, Er-nesto Hinrichs O, Martin Quijada FA, et al. Ictericia obstructiva secundaria a tumor de células granulares de la vía biliar extrahepá-tica. Rev Chil Cir [Internet]. 2011 Oct [citado 14 Dic 2018];63(6):[aprox. 4 p.]. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0718-40262011000600014&lng=es
Wang L, Zhu F, Shi H, Shanxian L, Shen W. Diagnosis of a granular cell tumour at the abdominal wall using fine needle aspiration cytology and histology: Case report. J Intern Med Res [Internet] 2015 May [citado 13 Dic 2018];43(4):[aprox. 5 p.]. Disponible en: https://doi.org/10.1177/0300060515583079
Deguchi Y, Iwahashi N, Horiuchi Y, Ikeji-ma M, Tanaka T, Ino K, et al. Non-neural granular cell tumor of the uterine corpus mimicking uterine leiomyoma: A case report. Mol Clin Oncol [Internet] 2017 Sep [citado 14 Dic 2018];7(3):[aprox. 4 p.]. Dis-ponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530305/.
Choudhary Z, Gupta P, Malhotra P, Bhardwaj M, Sharma PK. Granular Cell Tu-mour of the Chest Wall: FNA Diagnosis with a Review of Literature and Elaboration of Cyto-logical Mimickers. J Clin Diagn Res [Internet]. 2017 Aug [citado 14 Dic 2018];11(8):[aprox. 3 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620781/.
Singh M, Singh AK, Shubham S, Maan P, Chauhan U. Malignant Granular Cell Tumour Presenting as a Paravertebral Mass in an Ad-olescent Male-A Rare Presentation of an Un-common Tumour. J Clin Diagn Res [Internet] 2017 Feb [citado 14 Dic 2018];11(2):[aprox. 2 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376884/.
Chan Park W, Hye Choi S, Soo Lee Y. Granular Cell Tumor of the Thyroid Gland: A Case Report and Review of the Literature. Korean J Endocr Surg [Internet]. 2015 Mar [citado 14 Dic 2018];15(1):[aprox. 5 p.]. Disponible en: https://synapse.koreamed.org/search.php?where=aview&id=10.16956/kjes.2015.15.1.20&code=0219KJES&vmode=PUBREADER