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Latinoamericana de lnfectología Pediátrica.
Órgano de la Asociación Mexicana de
Infectología Pediátrica, A.C.
Órgano difusor de la Sociedad Española
de lnfectología

2019, Number 1

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Rev Latin Infect Pediatr 2019; 32 (1)

Powassan virus: a seldom studied flavivirus transmitted by ticks

Zúñiga CIR, Lozano JC

Language: Spanish
References: 7
Page: 11-14
PDF size: 134.22 Kb.


ABSTRACT

The most common clinical presentations of human diseases caused by POWV infection are encephalitis, meningoencephalitis and aseptic meningitis, with an incubation period ranging from eight to 34 days. The Powassan virus is transmitted by ticks, specifically the species Ixodes cookei, marxi and scapularis. There are two lineages of the Powassan virus, lineage 1 and lineage 2; both are capable of causing human diseases. POWV infections in humans typically involve febrile diseases followed by neurological involvement, resulting in a 10% mortality rate, with permanent and severe neurological sequelae in 50% of survivors. Long-term neurological sequelae in patients who survive POWV encephalitis include hemiplegia, muscle atrophy, severe chronic headaches and memory problems. Migration of mammals and the movement of warmer temperatures circulated the virus, consequently increasing its incidence. Other factors for the spread of the Powassan virus are the increased population of white-tailed deer and migratory birds, which propagate and introduce ticks to new regions.


REFERENCES

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  2. Hermance M, Thangamania S. Tick saliva enhances Powassan virus transmission to the host, influencing its dissemination and the course of disease. Journal of Virology. 2015; 89 (15): 7852-7860.

  3. Fatmi S, Zehra R, Carpenter D. Powassan virus a new reemerging tick-borne disease. Front Public Health. 2017; 5 (342): 1-12.

  4. CDC. Powassan Virus Website. Disponible en: http://www.cdc.gov/powassan/ [Consultado el 5 de enero de 2016].

  5. Pastula D, Smith D, Beckham D, Tyler K. Four emerging arboviral diseases in North America: Jamestown Canyon, Powassan, chikungunya, and Zika virus diseases. J Neurovirol. 2016; 22: 257-260.

  6. Hermance M, Santos R, Kelly B, Valbuena G, Thangamani S. Immune cell targets of infection at the tick-skin interface during Powassan virus transmission. PLoS One. 2016; 11 (5): 1-11.

  7. Hermance M, Thangaman S. Powassan virus: an emerging arbovirus of public health concern in North America. Vector Borne Zoonotic Dis. 2017; 17 (7): 453-462.




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