2019, Number 2
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Gac Med Mex 2019; 155 (2)
Enfermedad periodontal como factor de riesgo adicional asociado con nacimiento pretérmino en México: un estudio de casos y controles
Pérez-Molina JJ, González-Cruz MJ, Panduro-Barón JG, Santibáñez-Escobar LP, Quezada-Figueroa NA, Bedolla-Barajas M
Language: Spanish
References: 25
Page: 143-148
PDF size: 213.08 Kb.
ABSTRACT
Introduction: Substances related to microorganisms involved in periodontal disease can reach the maternal-fetal interface via
the hematogenous route and stimulate uterine contractility.
Objective: To determine the association between periodontal disease
and preterm birth.
Method: Case-control study in 343 preterm and 686 full-term pregnant women. Gestational age was
calculated based on the date of the last menstrual period and confirmed with Capurro and Ballard methods. Periodontal disease
was diagnosed according to the depth of the space between the tooth root and the gum. The association was measured
with logistic regression.
Results: Maternal age of the cases was 23.8 ± 6.7 years, and 23.2 ± 6.7 in the controls. Periodontal
disease was present in 66.8% of cases and 40.5% of controls. The factors associated with preterm birth were
periodontal disease (Odds ratio [OR] = 2.26), history of preterm birth (OR = 4.96), unplanned pregnancy (OR = 2.15) poor
prenatal control (OR = 2.53), urinary tract infection (OR = 2.22), preeclampsia (OR = 4.49), premature rupture of membranes
(OR = 2.59) and caesarean section delivery (OR = 9.15).
Conclusion: Periodontal disease in pregnancy was an independent
risk factor for preterm birth.
REFERENCES
Ananth CV, Vintzileos AM. Epidemiology of preterm birth and its clinical subtypes. J Matern Fetal Neonatal Med. 2006;19:773-782.
Purish SE, Gyamfi-Bannerman C. Epidemiology of preterm birth. Semin Perinatol. 2017;41:387-393.
Goldenberg RL, Culhane JF, lams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008;371:75-84.
Pérez-Molina J, Quezada-López C, Panduro-Barón G, Castro-Hernández JF. Factores de riesgo materno asociados con muerte fetal en nacimientos pretérmino en un hospital público del occidente de México. Rev Invest Clin. 2012;64:330-335.
Xiong X, Bueckens P, Fraser WD, Beck J, Offenbacher S. Periodontal disease and adverse pregnancy outcomes: a systematic review. BJOG. 2006;113:135-143.
Offenbacher S, Katz V, Fertik G, Collins J, Boyd D, Maynor G, et al. Periodontal infection as a possible risk factor for preterm low birth weight. J Periodontol. 1996;67:1103-1113.
Jeffcoat MK, Geurs NC, Reddy MS, Cliver SP, Goldenberg RL, Hauth JC. Periodontal infection and preterm birth: results of a prospective study. J Am Dent Assoc. 2001;132 875-880.
Ofenbacher S, Boggess KA, Murtha AP, Jared HL, Lieff S, McKaig RG, et al. Progressive periodontal disease and risks of very preterm delivery. Obstet Gynecol. 2006;107 29-36.
Siqueira FM, Cota LO, Costa JE, Haddad JP, Lana AM, Costa FO. Intrauterine growth restriction, low birth weight, and preterm birth: adverse pregnancy outcomes and their association with maternal periodontitis. J Periodontol. 2007;78:2266-2276.
Pulikottil-Shaju J, Nath S. Periodontitis among poor rural Indian mothers increases the risk of low birth weight babies: a hospital-based case control study. J Periodontal Implant Sci. 2014;44:85-93.
Wood S, Frydman A, Cox S, Brant R, Needoba S, Eley B, et al. Periodontal disease and spontaneous preterm birth: case control study. BMC Pregnancy Childbirth. 2006;6:24.
Lohsoonthron V, Kungsadalpipob K, Chanchareonsook P, Limpongsanurak S, Vanichjakvong O, Sutdhibhisal S, et al. Is maternal periodontal disease a risk factor for preterm birth? Am J Epidemiol. 2009; 169:731-739.
Calabrese N, Calabrese A, Nibali L, Rosati A, Fiengo S, Di-Renzo GC. Is there any association between periodontitis and preterm low birth weight? J Matern Fetal Neonatal Med. 2010;23:1288-1293.
Newman TB, Browner WS, Cummings SR, Hulley SB. Designing an observational study: cross-sectional and case-control studies. En: Hulley SB, Cummings SR, Browner WS, Grady D, Hearst N, Newman TB, editores. Designing clinical research an epidemiologic approach. EE. UU.: Lippincott Williams & Wilkins; 2001.
Highfield J. Diagnosis and classification of periodontal disease. Aust Dent J. 2009;54:S11-S26.
Capurro H, Konichezky S, Fonseca D, Caldeyro-Barcia R. A simplified method for diagnosis of gestational age in the newborn infant. J Pediatr. 1978;93:120-122.
Ballard JL, Khoury JC, Wedif K, Wang L, Eilers-Walsman BL, Lipp R. New Ballard score, expanded to include extremely premature infants. J Pediatr. 1991;119:417-423.
Cerda J, Villarroel L. Evaluación de la concordancia inter-observador en investigación pediátrica: coeficiente de Kappa. Rev Chil Pediatr. 2008;79:54-58.
Norma Oficial Mexicana NOM-007-SSA2-1993, atención de la mujer durante el embarazo, parto y puerperio y del recién nacido. Criterios y procedimientos para la prestación del servicio. México: Diario Oficial de la Federación 1994 Oct 31.
Adimark. El nivel socio económico Esomar. Manual de Aplicación. Chile; 2000.
Pérez-Molina JJ, Cobián-López B, Silva-Maciel CA. Factores de riesgo materno y nacimiento pretérmino en un hospital público del occidente de México. Ginecol Obstet Mex. 2004;72:142-149.
Meqa K, Dragidella F, Disha M, Sllamniku-Dalipi Z. The association between periodontal disease and preterm low birthweight in Kosovo. Acta Stomatol Croat. 2017;51:33-40.
López NJ, Smith PC, Gutierrez J. Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: a randomized controlled trial. J Periodontol. 2002;73:911-924
Moore S, Randhawa M, Ide M. A case-control study to investigate an association between adverse pregnancy outcome and periodontal disease. J Clin Periodontol. 2005;32:1-5.
Zi MY, Longo PL, Bueno-Silva B, Mayer MP. Mechanisms involved in the association between periodontitis and complications in pregnancy. Front Public Health. 2015;29:2:290.