2017, Number 4
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Enf Infec Microbiol 2017; 37 (4)
Streptococcus uberis as an emergent nosocomial pathogen in the Intensive Care Unit
Rosales MGF, Mendoza NJA, Pérez RSG
Language: Spanish
References: 10
Page: 125-127
PDF size: 141.19 Kb.
ABSTRACT
Each year, emerging strains appear, increasing health care associated infection mortality. Seven cases of infections
related to an outbreak due to
Streptococcus uberis in an Intensive Care Unit (ICU) are presented.
Material and Methods. Case series, carried out in Hospital ISSSTECALI Mexicali, B.C., Mexico. Clinical record data
were collected from patients infected with
Streptococcus uberis. Multivariate analysis was performed, Pearson
correlation, covariance, attack rate and lethality were estimated.
Results. During 2016 there were seven cases of pneumonia in the ICU, attack rate 0.1247/1000 discharges, average
age 69 years, predominantly male gender (71%). Associated comorbidities chronic degenerative diseases. Five
events of ventilator-associated pneumonia (71%). The bacterial phenotype of
S. uberis showed two multidrug resistant
strains. There was a direct correlation between advanced age and days of hospital stay as factors of poor prognosis,
superinfection is favored by other nosocomial pathogens. The lethality was 0.0712/1000 discharges. Average hospital
stay 28 days.
Conclusions. S. uberis associated infections are due to the selection of strains in the icu. Predispose to superinfection
by aggressive and opportunistic pathogens with a poor prognosis. It generates an increase in the lethality rate associated
with the antibiotic resistance index.
REFERENCES
Di Domenico, E.G., Toma, L., Prignano, G., Pelagalli, L., Police, A., Cavallotti, C., Torelli, R., Sanguinetti, M. y Ensoli, F., “Misidentification of Streptococcus uberis as a human pathogen: a case report and literature review”, Int J Infect Dis, 2015, 33: 79-81.
Girard, R., Perraud, M., Pruss, A., Savey, A., Tikhomirov, E., Thuriaux, M. et al., Prevención de las infecciones nosocomiales, guía práctica, 2a ed., Organización Mundial de la Salud, 2002, pp. 1-65.
Blanquer, J., Aspa, J., Anzueto, A., Ferrer, A., Gallego, M., Rajas, O. et al., “Normativa separ: neumonía nosocomial”, Arch Bronconeumol, 2011, 47 (10): 510-520.
Vélez-Montoya, R., Rascón, D., Mieler, W., Fromow, J. y Morales, V., “Case report: intravitreal ampicillin sodium for antiobiotic-resistant endophtalmitis: Streptococcus uberis first human intraocular infection report”, J Ophthalmol, 2010 (1): 1-4.
Watts, J. y Yancey, R., “Identification of veterinary pathogens by use of commercial identification systems and new trends in antimicrobial susceptibility testing of veterinary pathogens”, Clin Microbiol Rev, 1994, 7 (3): 346-355.
Huertas-Franco, V. y Lacayo-Pallais, M., “Neumonia por Stenotrophomonas maltophila”, Acta Med Costarric, 2014, 56 (1): 27-30.
Haenni, M., Galofaro, L., Ythier, M., Giddey, M., Majcherczyk, P., Moreillion, P. et al., “Penicillin-binding protein gene alteration in Streptococcus uberis isolates presenting decreased susceptibility to penicillin”, Antimicrob Agents Chemother, 2010, 54 (3): 1140-1145.
Haenni, M., Saras, E. y Madec, J., “Demonstration of a shift towards penicillin resistance in the Streptococcus uberis population”, J Med Microbiol, 2010, 1: 993-995.
Luna, C., Monteverde, A., Rodríguez Apezteguia, C., Zabert, G., Ilutovich, S. et al., “Neumonía intrahospitalaria: guía clínica aplicable a Latinoamérica preparada en común por diferentes especialistas”, Arch Bronconeumol, 2005, 41 (8): 439-456.
Upadhyay, S. y Pesola, G.R., “Streptococcus uberis, an unusual cause of community acquired pneumonia”, Am J Respir Crit Care Med, 2012, 185: A6119.