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2019, Number 1

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RIC 2019; 98 (1)

Delayed hemolytic transfusion reaction by anti-E alloantibody

Ali PNA, Matos BAA, Rodríguez RM

Language: Spanish
References: 12
Page: 98-105
PDF size: 122.75 Kb.


ABSTRACT

We present the case of a 47-year-old woman, blood group O Rh D positive, G4P2A2, with no transfusion history, which required surgical intervention due to bleeding uterine fibroma. The pretransfusional tests were compatible, transfusing two concentrates of red blood cells, without presenting clinical manifestations; after seven days, he presented a haemolytic crisis, with abrupt fall in hematological parameters, cutaneous-mucosal pallor and icterus. The immunohematological studies were positive; the patient's blood sample was incompatible with a son, husband and the transfused red blood cells. Six months later, an anti-E alloantibody (128 dilutions) was identified in the patient. It is concluded that the patient was alloimmunized during her pregnancies with an anti-E antibody, where the blood transfusion was the antigenic stimulus causing the late hemolytic transfusion reaction.


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