2018, Number 2
Erectile dysfunction, testosterone levels and its relationship with the presence of varicocele
Language: Spanish
References: 18
Page: 81-88
PDF size: 677.99 Kb.
ABSTRACT
Introduction: The relation of varicocele with erectile dysfunction and testosterone concentration has not been fully clarified. Objective: To determine the existing correlation among the presence of varicocele, plasma levels of testosterone and erectile dysfunction. Methods: A cross-sectional study was conducted in Pinar del Río province from 2014 to 2017. The correlation among the presence of varicocele and erectile dysfunction was established. Testosterone levels were compared in patients with and without varicocele. For the categorized variables, the chi-square test and the disparity ratio (Odds ratio) were used in the analysis. The quantitative variables were compared with the Student's t-test. The analyzes were performed with the SPSS software with a 95% of certainty. Results: The prevalence of erectile dysfunction in patients with varicocele was 38.6% and in those who did not have it, it was 26.1%. The Chi square test showed a significant association between both entities p꞊0.01 and the disparity ratio showed a slight increase in the risk of suffering from erectile dysfunction in the case of varicocele, OR- 1.7 IC (95%) 1, 14- 2.78. The mean serum testosterone concentration was lower in patients with varicocele (11.8 versus 16.1). The Student´s t- test showed a significant difference in both groups in relation to the determinations of this hormone p = 0.00. Conclusions: These findings suggest that varicocele may be involved in the occurrence of erectile dysfunction due to decreased levels of testosterone.REFERENCES
Jun Wang, Shu-Jie Xia, Zhi-Hong Liu, Le Tao, Ji-Fu Ge, Chen-Min Xu. Inguinal and subinguinal micro-varicocelectomy, the optimal surgical management of varicocele: a meta-analysis. Asian Journal of Andrology. 2015 [cited 2017 May 15];17:74-80. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C4291882/
Ali A Dabaja, Marc Goldstein. When is a varicocele repair indicated: the dilemma of hypogonadism and erectile dysfunction? Asian Journal of Andrology. 2016 [cited 2017 May 15];18:213-6. Disponible en: http://www.ajandrology.com/article.asp?issn= 1008- 682X %3Byear %3D2016 %3Bvolume%3D18 %3Bissue %3D2 %3Bspage %3D213 %3 Bepage %3D216 %3Baulast %3DDabaja
Selahittin Çayan, Muammer Kendirci, Önder Yaman, Ramazan Aşçı, İrfan Orhan, Mustafa Faruk Usta, et al. Prevalence of erectile dysfunction in men over 40 years of age in Turkey: Results from the Turkish Society of Andrology Male Sexual Health Study Group. Turk J Urol. 2017 [cited 2017 May 15];43(2):122-9. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C5503428/
Hajar Khosravanian, Mazdak Razi, Farah Farokhi, Narges Khosravanian. Simultaneous Administration of Dexamethasone and Vitamin E Reversed Experimental Varicocele-induced Impact in testicular tissue in Rats; Correlation with Hsp70-2 Chaperone Expression. Int Braz J Urol. 2015 [cited 2017 May 15];41(4):773-90. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C4757008/
Ozturk MI, Koca O, Keles MO. The impact of unilateral experimental rat varicocele model on testicular histopathology, Leydig cell counts, and intratesticular testosterone levels of both testes. Urol J. 2013 [cited 2017 May 15];10:973-80. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C4415645/