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2018, Number 2

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Rev cubana med 2018; 57 (2)

Circadian patterns of the arterial pressure in hypertensive patients with left ventricular hypertrophy and their relation with insulin resistance

León AJL, De Armas AAL, Calderín BRO, Hidalgo CT, Yanes QMÁ, Curbelo LM

Language: Spanish
References: 26
Page: 1-11
PDF size: 343.08 Kb.


ABSTRACT

Introduction: Left ventricular hypertrophy is one of the complications of arterial hypertension. The verification of the circadian pattern of the arterial pressure is essential in the comprehensive assessment to the hypertensive patient, but there is no enough evidence that relates left ventricular hypertrophy, the different circadian patterns of the arterial pressure and insulin resistance.
Objective: To evaluate the behaviour of the arterial pressure´s circadian patterns in hypertensive patients with left ventricular hypertrophy and its relation with insulin resistance.
Methods: Descriptive and cross-sectional research in 46 hypertensive patients with left ventricular hypertrophy to whom it was carried out an ambulatory monitoring of the arterial pressure, glycaemia and insulin serum in fasting, and calculation of the HOMA. There were correlated the different circadian patterns of the arterial pressure with the presence or not of insulin resistance and under control of the arterial pressure.
Results: The sample was constituted by a 54,3 % of women, and a 45,7 % of men; 52,2 % of them were between 45 to 59 years and 30,4 % of those were of 60 years or more. 87 % did not have control of their arterial pressure and 56,5 % had insulin resistance. 41,3 % in dipper, 32,6 % in non-dipper, 15, 2 % in marked dipper and 10,9 % in inverse dipper. HTA was present during awakening in 14 patients (30,4 %), and this was statistically significant in its relation with the insulin resistance (p=0,022); but not like that in relation to the control of the arterial pressure (32,5 %, p=0,398).
Conclusions: A major number of patients met abnormal circadian patterns of the arterial pressure, without having statistical significance, except for the HTA to the awakening in relation to the insulin resistance; but not with the control of the arterial pressure.


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