2018, Number 2
<< Back Next >>
Rev cubana med 2018; 57 (2)
Neurological complications in critically ill pregnant women
Garzón CL, Gómez VN, Riol LJM, Olivera LIR
Language: Spanish
References: 33
Page: 1-10
PDF size: 115.33 Kb.
ABSTRACT
Introduction: Obstetric patients can present numerous complications that put in
danger their lives, and they need of admission in intensive care units.
Objective: To characterize in a clinical way the critically ill pregnant women with
neurological complications.
Methods: An observational, descriptive, retrospective study was conducted in "
Hermanos Ameijeiras " Clinical-Surgical Hospital during the period from January,
2007 to December, 2016. There was carried out the calculation of absolute and
relative frequencies for the analysis of the data; there were applied measures of
central (average) trends and dispersion (range), and to know the possible
association between the qualitative variables the Chi-square´s Test was performed
with a significance of p < 0.05.
Results: The neurological complications appeared in 33,3 % of the patients and
the most frequent were: eclampsia (65,7 %), cerebral infarction (9,0 %) and
cerebral venous thrombosis (8,6 %). Being a nulliparous women (51,4 %) and age
of more than 35 years (42,8 %) were the most common risk factors. Arterial
hypertension was the main pathological background and the association between
the neurological complications and the direct cause of the death (p=0.00043) was
demonstrated.
Conclusions: The neurological complications were frequent in critically ill pregnant
women and they constitute a direct cause of death. The most frequent complication
was eclampsia.
REFERENCES
Tettenborn B. Stroke and pregnancy. Neurol Clin. 2012 [cited 15 jul 2015];30(3):913-24.
Malvino E. Complicaciones neurológicas en el embarazo y el puerperio. 1ra ed. Buenos Aires: Editorial Corpus; 2015. p. 28-178.
David Sáez M, Paulo Fuentes S. Neurología y embarazo. Rev chil neuropsiquiatria. 2010 [citado 24 may 2015];48(4):279-91.
González L, Gómez R, Vélez G, Agudelo S. Características de la atención hospitalaria y su relación con la morbilidad materna extrema en Medellín, Colombia. 2012. Revista Panamericana de Salud Pública. 2014 [citado 10 may 2015];35(1):15.
Álvarez M, Salvador S, González G, Pérez R. Caracterización de la morbilidad materna extremadamente grave. Revista Cubana de Higiene y Epidemiología. 2010 [citado 10 may 2015];48(3):310-20.
Mariño Martínez C, Vargas D. Caracterización de la morbilidad materna extrema en el Instituto Materno Infantil-Hospital la Victoria [tesis]. Universidad Nacional de Colombia. 2010.
Amato R, Faneite P, Rivera C, Faneite J. Morbilidad materna extrema. Revista de Obstetricia y Ginecología de Venezuela. 2011 [citado 10 may 2015];71(2):112-17.
Reyes-Armas I, Villar A. Morbilidad materna extrema en el Hospital Nacional Docente Madre-Niño San Bartolomé, Lima, 2007-2009. Rev peru ginecol obstet. 2012 [citado 10 may 2015];58:273-84.
Acho-Mego SC, Salvador Pichilingue J, Díaz-Herrera JA, García-Meza M. Morbilidad materna extrema: admisiones gineco-obstétricas en las unidades de cuidados intensivos de un hospital general, Lima. Rev Per Ginecología-Obstet. 2011 [citado 10 may 2015];57:87.
Kumar S, Bansal D, Hota D, Jain M, Singh P, Pandey BL. Assessment clinical outcomes and prescribing behavior among patients with severe preeclampsia and eclampsia: An Indian experience. Indian J Pharmacol. 2014 [cited 12 may 2015];46(1):18-23.
Schenone MH, Miller D, Samson J, Mari G. Eclampsia characteristics and outcomes: A comparison of two eras. J Pregnancy. 2013 [cited 18 may 2015];17:63.
Fong A, Chau C, Pan D, Adeboye D. Clinical morbidities, trends, and demographics of eclampsia a population-based study. Am J Obstet Gynecol. 2013 [cited 12 jul 2014];209(3):15.
Kittner S, Stern B, Feeser B, Hebel J, Nagey D, Buchholz D, et al. Pregnancy and the risk of stroke. N Engl J Med. 1996 [cited 10 aug 2015];335(11):768-74.
Sibai B, Coppage K. Diagnosis and management of women with stroke during pregnancy/postpartum. Clin Perinatol. 2004 [cited 10 ago 2015];31(4):853-68.
Moatti Z, Gupta M, Yadava R, Thamban S. A review of stroke and pregnancy: incidence, management and prevention. Eur J Obstet Gynecol Reprod Biol. 2014 [cited 10 ago 2015];181:20-7.
Awada A, Rajeh S, Duarte R, Russell N. Stroke and pregnancy. Int J Gynaecol Obstet. 1995 [cited 10 aug 2015];48(2):157-61.
Gulati D, Strbian D, Sundararajan S. Cerebral venous thrombosis diagnosis and management. Stroke. 2014 [citado 19 ene 2016];45:16-18.
Coutinho JM, Ferro JM, Zuurbier SM, Mink MS, Canhão P, Crassard I, et al. Thrombolysis or anticoagulation for cerebral venous thrombosis: rationale and design of the TO-ACT trial. International Journal of Stroke. 2013 [citado 19 ene 2016];8:135-40.
Zuluaga IM, Massaro M, Augusto Franco C. Trombosis de senos venosos cerebrales: epidemiología, características clínicas, imagenología y pronóstico. Biomédica. 2015 [citado 19 ene 2016];35:196-203.
Myers J, Baker P. Hypertensive diseases and eclampsia. Curr Opin Obstet Gynecol. 2002 [cited 10 ago 2015];14:119-25. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24433516
Lugo A, Álvarez A, Rodríguez A. Factores epidemiológicos de la hipertensión en el embarazo. Toko-Gin Pract. 1999 [citado 10 ago 2015];61:317-20.
Soli SB. Presentación y evolución de las pacientes ingresadas en la Unidad de Cuidados Intensivos con diagnóstico de Pre eclampsia-eclampsia [tesis]. Universidad Nacional de Rosario. 2013.
Chaturvedi S, Randive B, Mistry N. Availability of treatment for eclampsia in public Health Institutions in Maharashtra. J Health Popul Nutr. 2013 [cited 13 may 2015];31(1):86-95.
Zwart JJ, Richters A, Ory F, De Vries JL. Eclampsia in the Netherlands. Obstet Gynecol. 2008 [cited 10 ago 2015];112(4):820-7.
Sánchez MA. Factores de riesgo para pre eclampsia/eclampsia en mujeres atendidas en el Hospital Provincial General de Latacunga en el período comprendido entre enero 2008 a enero 2009 [tesis]. Escuela Superior Politécnica de Chimborazo- Ecuador. 2010.
Duckitt K, Harrington D. Risk factors for pre-eclampsia at antenatal booking: a systematic review of controlled studies. BMJ. 2005 [cited 10 ago 2015];330(7491):565.
Hovsepian DA, Sriram N, Kamel H, Fink ME, Navi BB. Acute cerebrovascular disease occurring after hospital discharge for labor and delivery. Stroke. 2014 [cited 10 ago 2015];45(7):1947-50.
Ros HS, Lichtenstein P, Bellocco R, Petersson G, Cnattingius S. Pulmonary embolism and stroke in relation to pregnancy: how can high-risk women be identified? American Journal of Obstetrics and Gynecology. 2002 [cited 10 ago 2015];186(2):198-203.
Lin S, Hu C, Lin H. Increased risk of stroke in patients who undergo cesarean section delivery: a nationwide population based study. Am J Obstet Gynecol. 2008 [cited 10 ago 2015];198(4):391.
Eslava Schmalbach J, Navarro Vargas R, Sabogal D. The evidence that shows that stroke and cesarean section are associated needs to be critically reviewed. Am J Obstet Gynecol. 2009 [cited 10 ago 2015];200(4):15.
Cabrera Naranjo F, González Hernández A, Lagoa Labrador I, Fabre Pi O. Trombosis de senos venosos cerebrales en el diagnóstico diferencial de la hipertensión intracraneal idiopática en mujeres jóvenes obesas: ¿un problema real? Rev Neurol. 2013 [citado 19 ene 2016];56(8):420-4.
James AH, Bushnell CD, Jamison MG, Myers ER. Incidence and risk factors for stroke in pregnancy and the puerperium. Obstetrics and Gynecology. 2005 [cited 20 may 2015];106(3):509-16.
Ferentz KS, Nesbitt LS. Common problems and emergencies in the obstetric patient. Prin Care Clin Office Pract. 2006 [cited 21 jul 2015];33(3):727-50.