2018, Number 3
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Rev Cubana Hematol Inmunol Hemoter 2018; 34 (3)
Acquired hemophilia A. A case report
Alonso-Mariño OL, Alonso-Mariño AL
Language: Spanish
References: 11
Page: 1-3
PDF size: 250.78 Kb.
ABSTRACT
Acquired hemophilia A is a rare bleeding disorder characterized by the presence of
autoantibodies against circulating factor VIII (FVIII). It has been observed in a heterogeneous
group of entities that include, among others, malignant diseases; 32 % associated with urological
processes, where prostate cancer has the highest prevalence. We present a patient who was
treated at the Oncology Service of the Celestino Hernández Robau University Hospital with the
diagnosis of acquired hemophilia A in the course of a prostatic adenocarcinoma. A coagulation
study was carried out at the Institute of Hematology and Immunology where the presence of
factor VIII inhibitor was confirmed, confirming the diagnosis. Immunosuppressive treatment was
given with prednisone 1 mg/kg of weight, with a favorable evolution.
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