2006, Number 3
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Cir Cir 2006; 74 (3)
Strabismus-associated Parinaud syndrome
Moguel-Ancheita S, Ruiz-Morfín I, Pedraza-Jacob M
Language: Spanish
References: 15
Page: 147-151
PDF size: 168.35 Kb.
ABSTRACT
Objective: We undertook this study to describe the causes of Parinaud syndrome (PS) with diplopia to determine a topographic diagnosis and prognosis.
Methods: We studied patients with PS from January 1980 to January 2004 and reviewed causes and treatment. We identified all strabismus associated with PS.
Results: We included 18 patients with diplopia, 6 females and 12 males. Median age was 28 years old, SD 22 (10; CI 95%).
Results are strabismus related: III nerve palsy in 15 patients (79%), optical nerve damage in 8 (44.4%), VII nerve palsy in 3, IV nerve palsy 2, bilateral III nerve palsy 2, nystagmus 2, Foville syndrome 2, one-and-a-half syndrome (1). The following causes were reported: tumors (6), brain stroke (4), cranial trauma (3), neurocysticercosis (2). Orthoposition under botulinum toxin treatment was obtained in 1.72 ± 1.1 (0.65 CI 95%). Surgery was done in nine patients, and only one patient had spontaneous resolution of diplopia and PS.
Conclusions: It is important to identify the topographic diagnosis and prognosis of brain diseases such as the complete study of strabismus-related PS. In this way we can learn more about the extent of damage and can identify recurrences quickly in order to offer better control.
REFERENCES
1.Pierrot-Deseilligny CH, Chain F, Gray F, Serdaru M, Escourolle R, Lhermitte F. Parinaud’s syndrome: electro-oculographic and anatomical analyses of six vascular cases with deductions about vertical gaze organization in the premotor structures. Brain 1982;105:667-696.
2.Moguel-Ancheita S. Aplicaciones de toxina botulínica en estrabismo. Rev Mex Oftalmol 1997;71:194-200.
3.Glaser JS. Infranuclear disorders of eye movement. In: Tasman W, Jaeger EA, eds. Clinical Ophthalmology. Philadelphia: Lippincott-Raven;1995. pp. 47-48.
4.Daroff RB, Troost BT, Leigh RJ. Supranuclear disorders of eye movements. In: Tasman W, Jaeger EA, eds. Clinical Ophthalmology. Philadelphia: Lippincott-Raven;1995. pp. 15-17.
5.Iijima M, Hirata A, Tadano Y, Kamakura K, Nagata N. A case of vertical gaze palsy associated with a unilateral infarct in the talamomesencephalic junction on MR imaging. Rinsho Shinkeigaku 1994;34:356-360.
6.Hirayama K, Sakakibara R, Asahina M, Honma K, Shinotoh H. Paramedian dorsal syndrome of mesencephalic tegmentum. Rinsho Shingkeigaku 1993;33:733-739.
7.Wang SF, Spencer RF. Spatial organization of premotor neurons related to vertical upward and downward saccadic eye movements in the rostral interstitial nucleus of the medial longitudinal fasciculus (riMLF in the cat). J Comp Neurol 1996;366:163-180.
8.Mateos V, Campos DM, Colosia VP, Salas-Puig J, Fernández JM, Lahoz CH. Nuclear syndrome of the oculomotor nerve caused by a mesencephalic infarction confirmed by MRI. Arch Neurobiol (Madr) 1992;55:183-187.
9.Hattori S, Utsunomiya K. Isolated oculomotor nerve palsy caused by mesencephalic hemorrhage. Rinsho Shinkeigaku 1994;34:1021-1025.
10.Roig C, Gironell A, Marti-Vilata JL, Grau JM, Barraquer L. Nuclear oculomotor nerve syndrome due to mesencephalic infarction of hemorrhage. Five cases and a review of literature. Neurologia 1994;9: 224-232.
11.Takami T, Sakaguchi M, Murata K, Nakabayashi H, Nakagawa O, Kawasaki H. A case report of Weber’s syndrome associated with supranuclear vertical gaze palsy caused by the ipsilateral thalamomesencephalic lesion. No To Shinkei 1993;45:461-464.
12.Furiya Y, Uchiyama S, Shibagaki Y, Yamamoto K, Ichikawa H, Iwata M. A case of basilar artery occlusion associated with one-anda-half syndrome, paralytic pontine exotropia and WEBINO syndrome. No To Shinkei 1997;49:558-562.
13.Waga S, Okada M, Yamamoto Y. Reversibility of Parinaud syndrome in thalamic hemorrhage. Neurology 1979;29:407-409.
14.Wilhelm BJ, Wilhelm H, Moro S, Barbur JL. Pupil response components: studies in patients with Parinaud’s syndrome. Brain 2000;125: 2296-2307.
15.Moffie D, Ongerboer de Visser BW, Stefanko SZ. Parianud’s syndrome. J Neurol Sci 1983;58:175-183.