2018, Number 3
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Rev Cubana Estomatol 2018; 55 (3)
Exfoliative cheilitis: differential diagnosis and treatment
da Silva BCC, Leal CI, Batista SL, Teixeira OP, Costa MAM, Dantas SÉJ
Language: Portugués
References: 52
Page: 1-13
PDF size: 224.89 Kb.
ABSTRACT
Introduction: exfoliative cheilitis is an infrequent skin condition that occurs mostly
in women, affecting the skin of the lips. Though its etiology is unknown, it has been
associated to stress and anxiety, as well as to parafunctional habits. Diagnosis and
management are challenging, due to the clinical similarity between exfoliative
cheilitis and other lesions of the lips, since these are often recurrent.
Objective: describe two clinical cases of exfoliative cheilitis, focusing on the
differential diagnosis.
Case presentation: the first case was a white male 21-year-old patient who
reported having had a burning sensation on his lips associated to crust formation
for two years. The patient stated having been under treatment and being in good
general health. Complementary tests were indicated which did not reveal any
alteration. Thus, the hypothesis of exfoliative cheilitis was put forth. Incisional
biopsy was performed under local anesthesia, histopathological examination
confirming the clinical diagnosis of exfoliative cheilitis. Laser therapy was indicated,
but the treatment was not successful. The second case was a black female 43-yearold
patient presenting with spots and fissures on her lips, as well as itching.
Complementary tests were indicated which yielded normal values, and thus the
clinical diagnosis was actinic prurigo. Incisional biopsy performed under local
anesthesia led to the diagnosis of exfoliative cheilitis. The patient was treated with
topical corticosteroids, with regression of the lesion.
Conclusions: exfoliative cheilitis diagnosis and clinical management are
challenging, hence the need to make an accurate diagnosis, excluding other
conditions with the aid of complementary tests.
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