2019, Number 1
<< Back Next >>
Salud Mental 2019; 42 (1)
Social cognition and executive function in borderline personality disorder: evidence of altered cognitive processes
Zegarra-Valdivia JA, Chino VBN
Language: English
References: 68
Page: 33-41
PDF size: 382.97 Kb.
ABSTRACT
Introduction. Social cognition (SC) and executive function (EF) research in borderline personality disorder
(BPD) has proven to be controversial and lack of sufficient information about deficit patterns.
Objective.
Assess the contribution of SC and EF in the socio-emotional and cognitive patterns in BPD, as well as investigate
the possible relationships between SC, EF, and clinic features in BPD.
Method. The study evaluated 20
females with BPD in ambulatory hospitalization and 20 healthy women in social cognition (“Reading the mind
through the eyes” and the IOWA gambling task) and executive function (with the Wisconsin Card Sorting Test,
verbal fluency tasks; digit spam test and numbers-and-letters of the WAIS-III, Trail Making Test Form A and
B).
Results. The results show statistically-significant differences for the tasks evaluated in social cognition,
the theory of mind (u: 181,
p ‹ .001**), and the IOWA gambling task, score IOWA 4 (
p ‹ .004*), and IOWA 5
p ‹ .003*); and executive functioning, for example in the Wisconsin card sorting test, WCST1 were found (p ‹
.003*), WCST2 (
p ‹ .004*), WCST3 (
p ‹ .018*) or WCST4 (
p ‹ .003*). Digit span test and verbal fluency had
significant differences compared to controls.
Discussion and conclusion. The subdomains evaluated would
be good endophenotypes as well as specific cognitive processes for research and rehabilitation.
REFERENCES
American Psychiatric Association. (2013). Diagnostic and Stadistical Manual of Mental Disorders. Washington: American Psychiatric Association.
Andreou, C., Kelm, L., Bierbrodt, J., Braun, V., Lipp, M., Yassari, A. H., & Moritz, S. (2015). Factors contributing to social cognition impairment in borderline personality disorder and schizophrenia. Psychiatry Research, 229(3), 872-879. doi: 10.1016/j.psychres.2015.07.057
Arntz, A., Bernstein, D., Oorschot, M., & Schobre, P. (2009). Theory of mind in borderline and cluster-C personality disorder. The Journal of Nervous and Mental Disease, 197(11), 801-807. doi: 10.1097/NMD.0b013e3181be78fb
Arntz, A. & Haaf, J. T. (2012). Social cognition in borderline personality disorder: Evidence for dichotomous thinking but no evidence for less complex attributions. Behaviour Research and Therapy, 50(11), 707-718. doi: 10.1016/j. brat.2012.07.002
Arza, R., Díaz, M., López, C., Fernández, N., López, J. J., & Carrasco, J. L. (2009). Rehabilitación neuropsicológica en pacientes con trastorno límite de personalidad: una serie de casos. Actas Españolas de Psiquiatría, 37(4), 236- 239.
Baron-Cohen, S., Leslie, M., & Frith, U. (1985). Does the autistic child have a “theory of mind”?. Cognition, 21(1), 37-46. doi: 10.1016/0010-0277(85)90022-8
Baron-Cohen, S., Wheelwright, S., Hill, J., Raste, Y., & Plumb, I. (2001). The “Reading the Mind in the Eyes” Test revised version: A study with normal adults, and adults with Asperger syndrome or high-functioning autism. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 42(2), 241-251. doi: 10.1111/1469-7610.00715
Bechara, A. (2005). Decision making, impulse control and loss of willpower to resist drugs: A neurocognitive perspective. Nature Neuroscience, 8(11), 1458-1463. doi: 10.1038/nn1584
Bechara, A., Damasio, H., Tranel, D., & Damasio, A. (2005). The Iowa Gambling Task and the somatic marker hypothesis: Some questions and answers. Trends in Cognitive Science, 9(4), 159-62. doi: 10.1016/j.tics.2005.02.002
Bechara, A. (2004). The role of emotion in decision-making: Evidence from neurological patients with orbitofrontal damage. Brain and Cognition, 55(1), 30-40. doi: 10.1016/j.bandc.2003.04.001
Bechara, A., Damasio, A., Damasio, H., & Anderson, S. (1994). Insensitivity to future consequences following damage to human prefrontal cortex. Cognition, 50(1- 3), 7-12.
Brevers, D., Bechara, A., Cleeremans, A., & Noël, X. (2013). Iowa Gambling Task (IGT): twenty years after-gambling disorder and IGT. Frontiers in Psychology, 4, 665. doi: 10.3389/fpsyg.2013.00665
Cullen, K., Vizueta, N., Thomas, K., Han, G., Lim, K., Camchong, J., … & Schulz, C. (2011). Amygdala Functional Connectivity in Young Women with Borderline Personality Disorder. Brain Connectivity, 1(1), 61-71. doi: 10.1089/ brain.2010.0001
Damasio, A. (1994). El error de Descartes: La razón de las emociones. Chile: Andrés Bello.
De la Cruz, M. (2001). Test de Clasificación de Tarjetas de Wisconsin. Madrid: TEA.
Domes, G., Schulze, L., & Herpertz, S. C. (2009). Emotion recognition in borderline personality disorder-a review of the literature. Journal of Personality Disorders, 23(1), 6-19. doi: 10.1521/pedi.2009.23.1.6
Fernández-Abascal, E. G., Cabello, R., Fernández-Berrocal, P., & Baron-Cohen, S. (2013). Test-retest reliability of the “Reading the Mind in the Eyes” test: A oneyear follow-up study. Molecular Autism, 4(1), 33. doi: 10.1186/2040-2392-4-33
Fertuck, E., Jekal, A., Song, I., Wyman, B., Morris, M. C., Wilson, S. T., & Stanley, B. (2009). Enhanced’Reading the Mind in the Eyes’ in borderline personality disorder compared to healthy controls. Psychological Medicine, 39(12), 1979. doi: 10.1017/S003329170900600X
Fertuck, E. A., Lenzenweger, M. F., Clarkin, J. F., Hoermann, S., & Stanley, B. (2006). Executive neurocognition, memory systems, and borderline personality disorder. Clinical Psychology Review, 26(3), 346-375. doi: 10.1016/j. cpr.2005.05.008
Fonagy, P. & Bateman, A. (2008). The development of borderline personality disorder a mentalizing model. Journal of Personality Disorders, 22(1), 4-21. doi: 10.1521/pedi.2008.22.1.4
Forti, L. & Forti, A. (2012). Trastorno límite de la personalidad y conductas autolíticas. Revista Española de Medicina Legal, 38(4). doi: 10.1016/j.reml.2012.08.001
Franzen, N., Hagenhoff, M., Baer, N., Schmidt, A., Mier, D., Sammer, G., … & Lis, S. (2011). Superior Theory of Mind in borderline personality disorder: an analysis of interaction behavior in a virtual trust game. Psychiatry Research, 187(1-2), 224-233. doi: 10.1016/j.psychres.2010.11.012
Frick, C., Lang, S., Kotchoubey, B., Sieswerda, S., Dinu-Biringer, R., Berger, M., & Barnow, S. (2012). Hypersensitivity in borderline personality disorder during mindreading. PLoS ONE, 7(8), 4-11. doi: 10.1371/journal.pone.0041650
Gavilán-Ibáñez, J. M. & García-Albea, J. E. (2013). Theory of mind and language comprehension in schizophrenia. Psicothema, 25(4), 440-445. doi: 10.7334/ psicothema2012.357
Gottesman, I. & Gould, T. (2003). The Endophenotype concept in psychiatry: Etymology and Strategic Intentions. American Journal of Psychiatry, 160(4), 636-645. doi: 10.1176/appi.ajp.160.4.636
Grant, B. F., Chou, S. P., Goldstein, R. B., Huang, B., Stinson, F. S., Saha, T. D., Smith, S. M., Dawson, D. A., Pulay, A. J., Pickering, R. P., … Ruan, W. J. (2008). Prevalence, correlates, disability, and comorbidity of DSM-IV borderline personality disorder: results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions. The Journal of clinical psychiatry, 69(4), 533-45.
Grosjean, B. & Tsai, G. (2007). NMDA neurotransmission as a critical mediator of borderline personality disorder. Journal of Psychiatry & Neuroscience, 32(2), 103-115.
Gvirts, H., Harari, H., Braw, Y., Shefet, D., Shamay-Tsoory, S., & Levkovitz, Y. (2012). Executive functioning among patients with borderline personality disorder and their relatives. Journal of Affective Disorders, 143(1-3), 261-264. doi: 10.1016/j.jad.2012.05.007
Hagenhoff, M., Franzen, N., Koppe, G., Baer, N., Scheibel, N., Sammer, G., … & Lis, S. (2013). Executive functions in borderline personality disorder. Psychiatry Research, 210(1), 224-231. doi: 10.1016/j.psychres.2013.05.016 Agregué doi
Hernández, R., Fernández, C., & Baptista, P. (2010). Metodología de la Investigación. México: Mc Graw Hill.
Homberg, J. (2012). Serotonin and decision making processes. Neuroscience and Biobehavioral Reviews, 36(1), 218-236. doi: 10.1016/j.neubiorev.2011.06.001
Hughes, A. E., Crowell, S. E., & Coan, J. A. (2012). A developmental neuroscience of borderline pathology: emotion dysregulation and social baseline theory. Journal of abnormal child psychology, 40(1), 21-33. doi: 10.1007/s10802-011-9555-x
Igarashi, H., Hasui, C., Uji, M., Shono, M., Nagata, T., & Kitamura, T. (2010). Effects of child abuse history on borderline personality traits, negative life events, and depression: A study among a university student population in Japan. Psychiatry Research, 180(2-3), 120-125. doi: 10.1016/j.psychres.2010.04.029
Jaichenco, V., Wilson, M., & Ruiz, A. (2007). “Evaluación del lenguaje”. In D. Burin, M. Drake, & P. Harris, (eds.), Evaluación neuropsicológica en adultos. Paidós: Argentina.
Jacob, A. G., Zvonik, K., Kamphausen, S., Sebastian, A., Maier, S., Philipsen, A., & Tüscher, O. (2013). Emotional modulation of motor response inhibition in women with borderline personality disorder: An fMRI study. Journal of Psychiatry and Neuroscience, 38(3), 164-172. doi: 10.1503/jpn.120029
Klengel, T., Pape, J., Binder, E. B., & Mehta, D. (2014). The role of DNA methylation in stress-related psychiatric disorders. Neuropharmacology, 80, 115-132. doi: 10.1016/j.neuropharm.2014.01.013
LeGris, J., Links, P. S., van Reekum, R., Tannock, R., & Toplak, M. (2012). Executive function and suicidal risk in women with Borderline Personality Disorder. Psychiatry Research, 196(1), 101-108. doi: 10.1016/j.psychres.2011.10.008
Leichsenring, F., Leibing, E., Kruse, J., New, A. S., & Leweke, F. (2011). Borderline personality disorder. The Lancet, 377(9759), 74-84. doi: 10.1016/S0140- 6736(10)61422-5
Lynch, T., Rosenthal, M., Kosson, D., Cheavens, J., Lejuez, C., & Blair, R. (2006). Heightened sensitivity to facial expressions of emotion in borderline personality disorder. Emotion, 6(4), 647-55. doi: 10.1037/1528-3542.6.4.647
Maurex, L., Zaboli, G., Ohman, A., Asberg, M., & Leopardi, R. (2010). The serotonin transporter gene polymorphism (5-HTTLPR) and affective symptoms among women diagnosed with borderline personality disorder. European Psychiatry, 25(1), 19-25. doi: 10.1016/j.eurpsy.2009.05.001
Maurex, L., Zaboli, G., Wiens, S., Asberg, M., Leopardi, R., & Ohman, A. (2009). Emotionally controlled decision-making and a gene variant related to serotonin synthesis in women with borderline personality disorder. Scandinavian Journal of Psychology, 50(1), 5-10. doi: 10.1111/j.1467-9450.2008.00689.x
McGowan, P. O. & Szyf, M. (2010). The epigenetics of social adversity in early life: Implications for mental health outcomes. Neurobiology of Disease, 39(1), 66- 72. doi: 10.1016/j.nbd.2009.12.026
McCloskeya, M., New, A., Siever, L., Goodman, M., Koenigsberg, H., Flory, J., & Coccaro, E. (2009). Evaluation of behavioral impulsivity and aggression task as endophenotypes of borderline personality disorder. Journal of Psychiatric Research, 43(12), 1036-1048. doi: 10.1016/j.jpsychires.2009.01.002
Mier, D., Lis, S., Esslinger, C., Sauer, C., Hagenhoff, M., Ulferts, J., … & Kirsch, P. (2013). Neuronal correlates of social cognition in borderline personality disorder. Social Cognitive and Affective Neuroscience, 8(5), 531-537. doi: 10.1093/scan/nss028
Miller, E. (2010). The prefrontal cortex and cognitive control. Nature reviews neuroscience, 1, 59-65. doi: 10.1038/35036228
Montero, I. & León, O. G. (2007). A guide for naming research studies in Psychology. International Journal of Clinical and Health Psychology, 7(3), 847-862.
Mueller, S. T. & Piper, B. J. (2014). The Psychology Experiment Building Language (PEBL) and PEBL Test Battery. Journal of Neuroscience Methods, 222, 250- 259. doi: 10.1016/j.jneumeth.2013.10.024
O’Neill, A., D’Souza, A., Samson, A. C., Carballedo, A., Kerskens, C., & Frodl, T. (2014). Dysregulation between emotion and theory of mind networks in borderline personality disorder. Psychiatry Research, 231(1), 25-32. doi: 10.1016/j.pscychresns.2014.11.002
Paris, J. (2008). Treatment of Borderline Personality Disorder: Guide to Evidence Based Practice. New York: Guilford.
Pope, H. G., Jonas, J. M., Hudson, J. I., Cohen, B. M., & Tohen, M. (1985). An empirical study of psychosis in borderline personality disorder. The American journal of psychiatry, 142(11), 1285-1290. doi: 10.1176/ajp.142.11.1285
Preißler, S., Dziobek, I., Ritter, K., Heekeren, H. R., & Roepke, S. (2010). Social Cognition in Borderline Personality Disorder: Evidence for Disturbed Recognition of the Emotions, Thoughts, and Intentions of others. Frontiers in behavioral neuroscience, 4, 8. doi: 10.3389/fnbeh.2010.00182
Robin, M., Pham-Scottez, A., Curt, F., Dugre-Le Bigre, C., Speranza, M., Sapinho, D., & Kedia, G. (2012). Decreased sensitivity to facial emotions in adolescents with Borderline Personality Disorder. Psychiatry Research, 200(2-3), 417-421. doi: 10.1016/j.psychres.2012.03.032
Roepke, S., Vater, A., Preißler, S., Heekeren, H. R., & Dziobek, I. (2012). Social cognition in borderline personality disorder. Frontiers in Neuroscience, 6, 1-12. doi: 10.3389/fnins.2012.00195
Sabbagh, M. (2004). Understanding orbitofrontal contributions to theory-of-mind reasoning: implications for autism. Brain and Cognition, 55(1), 209-219. doi: 10.1016/j.bandc.2003.04.002
Svaldi, J., Philipsen, A., & Matthies, S. (2012). Risky decision-making in borderline personality disorder. Psychiatry Research, 197(1-2), 112-118. doi: 10.1016/j. psychres.2012.01.014
Silvio, V. (2005). Funciones fronto-temporales en pacientes diagnosticados con trastorno límite de la personalidad. Archivos Venezolanos de Psiquiatría y Neurología, 15(104), 30-35.
Stevens, A., Burkhardt, M., Hautzinger, M., Schwarz, J., & Unckel, C. (2004). Borderline personality disorder: Impaired visual perception and working memory. Psychiatry Research, 125(3), 257-267. doi: 10.1016/j. psychres.2003.12.011
Tajima, K., Montes, A., García-Andrade, R. F., Casado, A., Carrasco, J. L., & Diaz-Marsá, M. (2009). Estudios de neuroimagen en el trastorno límite de la personalidad. Actas Espanolas de Psiquiatria, 37(3), 123-127.
Tajima, M., & de Anta, L. (2009). “Trastornos de Personalidad”. In M.Munárriz, P. García-Portilla, & M. Roca. Manual del Residente en Psiquiatría I. Asociación Española de Psiquiatría (AEN), la Sociedad Española de Psiquiatría (SEP) y la Sociedad Española de Psiquiatría Biológica (SEPB). Madrid: España.
Tebartz, L., Hesslinger, B., Thiel, T., Geiger, E., Haegele, K., Lemieux, L., … & Ebert, D. (2003). Frontolimbic brain abnormalities in patients with borderline personality disorder: a volumetric magnetic resonance imaging study. Biological Psychiatry, 54(2), 163-171.
Toplak, M. E., Sorge, G. B., Benoit, A., West, R. F., & Stanovich, K. E. (2010). Decision-making and cognitive abilities: A review of associations between Iowa Gambling Task performance, executive functions, and intelligence. Clinical Psychology Review, 30(5), 562-581. doi: 10.1016/j.cpr.2010.04.002
Unoka, Z., Fogd, D., Füzy, M., & Csukly, G. (2011). Misreading the facial signs: Specific impairments and error patterns in recognition of facial emotions with negative valence in borderline personality disorder. Psychiatry Research, 189(3), 419-425. doi: 10.1016/j.psychres.2011.02.010
Vaskinn, A., Antonsen, B. T., Fretland, R. A., Dziobek, I., Sundet, K., & Wilberg, T. (2015). Theory of mind in women with borderline personality disorder or schizophrenia: Differences in overall ability and error patterns. Frontiers in Psychology, 6, 1-7. doi: 10.3389/fpsyg.2015.01239
Villodre, R., Sánchez-Alfonso, A., Brines, L., Núñez, A., Chirivella, J., Ferri, J., & Noé, E. (2006). Fluencia verbal: estudio normativo piloto según estrategias de «agrupación» y «saltos» de palabras en población española de 20 a 49 años. Neurología, 21(3), 124-130. Wechsler, D. (1997). WAISS-III Manual. San Antonio: The Psychological Corporation.
Wolf, R., Sambataro, F., Vasic, N., Schmid, M., Thomann, P., Bienentreu, S., &
Wolf, N. (2011). Aberrant connectivity of resting-state networks in borderline personality disorder. Journal of psychiatry & neuroscience, 36(6), 402-411. doi: 10.1503/jpn.100150
Yee, L., Korner, A. J., McSwiggan, S., Meares, R. A., & Stevenson, J. (2005). Persistent hallucinosis in borderline personality disorder. Comprehensive Psychiatry, 46(2), 147-154. doi: 10.1016/j.comppsych.2004.07.032
Zanarini, M. (2000). Childhood experiences associated with the development of borderline personality disorder. Psychiatric Clinics of North America, 23(1), 89-101. doi: 10.1016/S0193-953X(05)70145-3