Martínez FY, Moreno MHR, Mendoza TY, Escalona GP, Otero NSA, Tamayo CA

Language: Spanish
References: 0
Page: 1134-1143
PDF size: 311.94 Kb.

ABSTRACT

One of the risks associated with pregnancy is advanced maternal age, which is considered in Cuba, from 35 years of age. At present, it constitutes the main indication reason for the prenatal cytogenetic diagnosis. A cross-sectional descriptive-retrospective study was conducted at the Medical Genetics Center of Granma province, with the aim of describing the cytogenetic prenatal diagnosis in pregnant women of advanced maternal age during the period 2013-2017. The universe consisted of 1544 patients, pregnant women with advanced maternal age who were diagnosed by amniocentesis between 16 and 20 weeks. In the period under study, 1544 prenatal cytogenetic studies were performed on a total of 2229 pregnant women with advanced maternal age (69%). During these five years of work a total of 1502 normal studies were obtained (97%) and the positive results were 42 studies representing 3%. Down syndrome showed a frequency of 45% (19/42) and the rest of the chromosomal anomalies found 55% (23/42). The advanced maternal age conditions from the preconceptional stage and during the evolution of the pregnancy, affectations in the fetal development and in its quality of life for what is recommended to develop and perfect informative and educational strategies on these subjects to the population at risk.