Demosthene SA, Fernández GRE, Iglesias GM, Travieso MM

Language: Spanish
References: 0
Page: 36-55
PDF size: 350.59 Kb.

ABSTRACT

Introduction. The irradiation of malignant lesions frequently produces lesions in the surrounding normal tissues. The pathophysiological bases of these lesions consists on a progressive obliterate endarteritis that derives in a hypocelular, hypovascular and hypoxic tissue. Hyperbaric oxygenation has been intended as part of the global treatment to these lesions. Although several authors report their benefit, in Cuba there are not studies that demonstrate their effectiveness. It becomes necessary to demonstrate how this therapy influences in the evolution of the patients. Method. It was carried out a retrospective, analytic, observational and the court study of 30 patients with diagnostic of radioinduced lesion, assisted in Hyperbaric Oxygenation Department of CIMEQ between 2010 and 2014, being analyzed the variables age, sex, lesion type, symptoms, clinical evolution and treatment efficacy. Results. There was a prevalence of masculine sex. Age average was 60 years-old. It was studied 14 cystitis, 4 proctitis, 8 radiodermitis/mucositis, 2 osteonecrosis and 5 neurological lesions´s patients. Hematuria was the most frequent symptom in cystitis, pain in proctitis and induration in radiodermitis. The 26% of patients obtained total improvement with the first treatment cycle. The therapeutic success was obtained in 96% of patients requiring for it from 20 to 80 treatment sessions. Conclusions. Hyperbaric oxygenation improves symptoms and clinical evolution of radioinduced lesion's patients.