2018, Number 1
Evolution in patients with compensated liver cirrhosis
Cruz HZD, Samada SM, Hernández PJC, Rodríguez RH, Pérez GT, Barroso ML
Language: Spanish
References: 0
Page: 22-35
PDF size: 262.29 Kb.
ABSTRACT
Introduction: Liver cirrhosis often appears as a silent disease, so diagnosis in the compensated phase is usually done through unspecific manifestations or laboratory findings. In the not compensated phase, it can make its onset with complications such as ascites, bleeding varices, and encephalopathy, among others. The aim of this study is to describe the evolution of patients with compensated liver cirrhosis from January 2000 to December 2012. Methods: The work includes a descriptive retrospective and longitudinal study of patients with compensated liver cirrhosis. 48 patients satisfied the inclusion and exclusion criteria with a mean of 6 years of follow-up, and an average age of 42,6 years. 30 of them 62, 5% were females and 18 of them 37,5%. were males. Results: In the initial evaluation, splenomegaly. 41, 7%, and esophageal varices, 37,5%, were the principal manifestations in portal hypertension, that increased in a significant way the final evaluation were 64,6% and 52,1% respectively. The most frequent relevant complications during the study were ascites 27,1% and icterus 22,9%. 37,5% of the patients were not compensated and 18,8% of them belonged to stage 4, according to Baveno V definitions and criteria. Conclusions: The manifestation of portal hypertension increased in a significant way, and approximately one third of the patients moved to the not compensated phase of the illness.