2019, Number 1
Cerebral vasculitis in a patient with rheumatoid arthritis treated with biologic anti-TNF alpha agents
Language: Spanish
References: 10
Page: 54-55
PDF size: 106.73 Kb.
ABSTRACT
Vasculitis is the inflammation and destruction of the walls of the blood vessels that leads to occlusion or the formation of aneurysms, with the resulting ischemic-hemorrhagic changes. The involvement of central nervous system vessels darkens the prognosis and can be serious. Being a multi-causal disease with similar clinical and imaging manifestations, the differential diagnosis is a challenge. Vasculitis can be primary, associated with connective tissue diseases, infections, neoplasms and drugs. We present a case of cerebral vasculitis in a patient with rheumatoid arthritis secondary to a biological anti-FNT alpha medication that progressed satisfactorily to treatment with corticosteroids and immunosuppressive drugs.REFERENCES
Guignard S, Gossec L, Bandinelli F, Dougados M. Comparison of the clinical characteristics of vasculitis occurring during anti-tumor necrosis factor treatment or not in rheumatoid arthritis patients: a systematic review of 2707 patients, 18 vasculitis. Clin Exp Rheumatol. 2008; 26 (3 suppl 49): S23-S29.
Charles PJ, Smeenk RJ, De Jong J, Feldmann M, Maini RN. Assessment of antibodies to double-stranded DNA induced in rheumatoid arthritis patient following treatment with infliximab a monoclonal antibody to tumor necrosis factor alpha: findings in open label and randomized placebo-controlled trials. Arthritis Rheum. 2000; 43 (11): 2383-2390.