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2018, Number 3

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Arch Inv Mat Inf 2018; 9 (3)

Relation between absence of fetal breathing movements and the presence of preterm delivery

Martínez ALM, Moreno SAA, Briones VC, Díaz de León PMA, Briones GJC

Language: Spanish
References: 30
Page: 85-90
PDF size: 114.12 Kb.


ABSTRACT

Objective: The aim of this study is to examine the relation between of absence of fetal breathing movements (FBM) and the presence of preterm delivery. Material and methods: We designed a prospective and descriptive study. The study group involved 120 hospitalized women with singleton pregnancies and threatened preterm labor between 24 and 36 weeks of gestation in a tertiary care hospital. Women were recruited for a single ultrasonography test to assess fetal FBM. We evaluated the presence of preterm birth within seven days of testing. Results: FBM were observed in 86 patients and considered absent in the remaining 34 patients. In those pregnancies with absent FBM, true labor with subsequent delivery occurred in 26 patients. Of the 86 pregnancies with FBM present, 83 continued for greater than seven days. We used χ2 to demonstrate that the absence of fetal breathing movement is a reliable indicator of preterm delivery (p less than 0.05). The observed sensitivity was 89.7%, specificity 91.2%, positive predictive value 76.5% and negative predictive value of 96.5%. The relative risk of preterm delivery according to the absence of FBM was 10.10 (95% CI 5.2-19.9). Conclusions: Ultrasonographic identification of absence of fetal breathing movements provides predictive information on the presence of preterm delivery and may be helpful in differentiating between true and false preterm labor.


REFERENCES

  1. Boots AB, Sanchez-Ramos L, Bowers DM, Kaunitz AM, Zamora J. The short-term prediction of preterm birth: a systematic review and diagnostic metaanalysis, Am J Obstet Gynecol, 2014; 210: 54.e1-10.

  2. Newton RE. Preterm labor, preterm premature of membrane and chorioamnionitis, Clin Perinatol, 2005; 32: 571-600.

  3. Obstetric Guideline 2A. Preterm Labour. British Columbia Reproductive Care Program, 2005. p. 1-18.

  4. Snegovskikh V, Park JS, Norwitz ER. Endocrinology of Parturition. Endocrinology of parturition, Endocrinol Metab Clin North Am, 2006; 35 (1): 173-191, viii.

  5. Besinger RE, Compton AA, Hayashi RH. The presence or absence of fetal breathing movements as a predictor of outcome in preterm labor, Am J Obstet Gynecol, 1987; 157: 753-757.

  6. Guía de Práctica clínica. Diagnóstico y manejo del parto pretérmino. México: Secretaría de Salud; 2009.

  7. Bloom SL, Yost NP, McIntire DD, Leveno KJ. Recurrence of preterm birth in singleton an twin pregnancies, Obstet Gynecol, 2001; 98: 379-385.

  8. Laughon SK, Albert PS, Leishear K, Mendola P. The NICHD consecutive pregnancies study: recurrent preterm delivery by subtype, Am J Obstet Gynecol, 2014; 210 (2): 131.e1-8.

  9. Yamashita M, Hayashi S, Endo M, Okuno K, Mimura K, Tachibana Y et al. Incidence and risk factors for recurrent spontaneous preterm birth: a retrospective cohort study in Japan, J Obstet Gynaecol Res, 2015; 41 (11): 1708-1714.

  10. Haas DM, Imperiale TF, Kirkpatrick PR, Klein RW, Zollinger TW, Golichowski AM, et al. Tocolytic therapy: a meta-analysis and decision analysis, Obstet Gynecol, 2009; 113 (3): 585-594.

  11. Kuhrt K, Smout E, Hezelgrave N, Seed PT, Carter J, Shennan AH. Development and validation of a tool incorporating cervical length and quantitative fetal fibronectin to predict spontaneous preterm birth in asymptomatic high-risk women, Ultrasound Obstet Gynecol, 2016; 47 (1): 104-109.

  12. Hezelgrave NL, Abbott DS, Radford SK, Seed PT, Girling JC, Filmer J et al. Quantitative fetal fibronectin at 18 weeks of gestation to predict preterm birth in asymptomatic high-risk women, Obstet Gynecol, 2016; 127 (2): 255-263.

  13. Berghella V, Saccone G. Fetal fibronectin testing for prevention of preterm birth in singleton pregnancies with threatened preterm labor: a systematic review and metaanalysis of randomized controlled trials, Am J Obstet Gynecol, 2016; 215 (4): 431-438.

  14. Deshpande SN, van Asselt AD, Tomini F, Armostrong N, Allen A, Noake C et al. Rapid fetal fibronectin testing to predict preterm birth in women with symptoms of premature labour: a systematic review and cost analysis, Health Technol Assess, 2013; 17 (40): 1-138.

  15. Foster C, Shennan AH. Fetal fibronectin as a biomarker of preterm labor: a review of the literature and advances in its clinical use, Biomark Med, 2014; 8 (4): 471-484.

  16. McLaren JS, Hezelgrave NL, Ayubi H, Seed PT, Shennan AH. Prediction of spontaneous preterm birth using quantitative fetal fibronectin after recent sexual intercourse, Am J Obstet Gynecol, 2015; 212 (1): 89.e1-5.

  17. Shimoya K, Hashimoto K, Shimizu T, Koyama M, Azuma C, Murata Y. Cervical fluid oncofetal fibronectin as a predictor of early ectopic pregnancy. Is it affected by blood contamination? J Reprod Med, 2002; 47 (8): 640-644.

  18. Berghella V, Palacio M, Ness A, Alfirevic Z, Nicolaides KH, Saccone G. Cervical length screening for prevention of preterm birth in singleton pregnancy with threatened preterm labor: systematic review and meta-analysis of randomized controlled trials using individual patient-level data, Ultrasound Obstet Gynecol, 2017; 49 (3): 322-329.

  19. van Baaren GJ, Vis JY, Wilms FF, Oudijk MA, Kwee A, Porath MM et al. Predictive value of cervical length measurement and fibronectin testing in threatened preterm labor, Obstet Gynecol, 2014; 123 (6): 1185-1192.

  20. Schmitz T, Maillard F, Bessard-Bacquaert S, Kayem G, Fulla Y, Cabrol D et al. Selective use of fetal fibronectin detection after cervical length measurement to predict spontaneous preterm delivery in women with preterm labor, Am J Obstet Gynecol, 2006; 194 (1): 138-143.

  21. Audibert F, Fortin S, Delvin E, Djemli A, Brunet S, Dubé J et al. Contingent use of fetal fibronectin testing and cervical length measurement in women with preterm labour, J Obstet Gynaecol Can, 2010; 32 (4): 307-312.

  22. Honest H, Bachmann LM, Sengupta R, Gupta JK, Kleijnen J, Khan KS. Accuracy of absence of fetal breathing movements in predicting preterm birth: a systematic review, Ultrasound Obstet Gynecol, 2004; 24: 94-100.

  23. Minguet R, Cruz P, Ruiz R, Hernández M. Incidencia de nacimientos pretérmino en el IMSS (2007-2012), Ginecol Obstet Mex, 2014; 82: 465-471.

  24. Agustsson P, Patel NB. The predictive value of fetal breathing movements in the diagnosis of preterm labour, Br J Obstet Gynaecol, 1987; 94: 860-863.

  25. Castle BM, Turnbull AC. The presence or absence of fetal breathing movements predicts the outcome of preterm labour, Lancet, 1983; 2: 471-473.

  26. Devoe LD, Youssef AE, Croom CS, Watson J. Can fetal biophysical observations anticipate outcome in preterm labor or preterm rupture of membranes?, Obstet Gynecol, 1994; 84: 432-438.

  27. Kanaan CM, O’Grady JP, Veille JC. Effect of maternal carbon dioxide inhalation on human fetal breathing movements in term and preterm labor, Obstet Gynecol, 1991; 78: 9-3.

  28. Markwitz W, Ropacka M, Breborowicz GH. Evaluation of fetal breathing movements in prognosis of preterm labor, Ginekol Pol, 2001; 72: 55-60.

  29. Schreyer P, Caspi E, Natan NB, Tal E, Weinraub Z. The predictive value of fetal breathing movement and Bishop score in the diagnosis of ‘‘true’’ preterm labor, Am J Obstet Gynecol, 1989; 161: 886-889.

  30. Senden IP, Owen P. Comparison of cervical assessment, fetal fibronectin and fetal breathing in the diagnosis of preterm labour, Clin Exp Obstet Gynecol, 1996; 23: 5-9.




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