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Órgano Oficial de Difusión Científica de la Federación Mexicana de Colegios de Ortopedia y Traumatología, A.C. (FEMECOT)

2018, Number 2

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Ortho-tips 2018; 14 (2)

Functional improvement in patients with gonarthrosis treated with intraarticular infiltration of hyaluronic acid versus hylan G-F 20

Nava-Tapia TM, Pérez-Atanasio JM, Vázquez-Morales E, King-Denis EE, Males-Hoyos J

Language: Spanish
References: 19
Page: 87-92
PDF size: 178.70 Kb.


ABSTRACT

Introduction: Osteoarthrosis is the most frequent chronic disease and the most important cause of disability in adults. There are numerous current treatment options, one of which is viscosupplementation. The objective is to compare the functionality according to the WOMAC scale the viscosupplementation with a low molecular hyaluronic acid vs hylan G-F 20. Method: Transverse study, patients with Grade II and III gonarthrosis of Kellgren and Lawrence treated by intraarticular infiltration with a low molecular hyaluronic acid (Suplasyn) or hylan G-F 20 (Synvisc) from October 2017 to February 2018, a weekly injection of 2 ml for a total of three doses. An initial WOMAC scale was measured and a two months WOMAC scale after the infiltration, as well as the analgesic ingestion prior to measurements. Bivariate analysis was performed for comparison between groups and correlation tests were applied, 95% confidence interval considering significant value p ‹ 0.05. Results: 98 patients, 48 infiltrates with a low molecular hyaluronic acid and 50 infiltrates with hylan G-F 20. Both groups have better WOMAC scale functionality, in the Synvisc group an average improvement of 7.24 points. In the Suplasyn group there was an improvement of 7.14 points, with a value of p ‹ 0.05 in both. Conclusion: There is a functional improvement in the WOMAC scale measurement in patients infiltrated with hylan G-F 20 and a low molecular hyaluronic acid two months after infiltration, however a no statistically significant difference in the functional improvement between a hyaluronic acid lower molecular weight and hylan is demonstrated, both of which seem to be equivalent.


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