Pascual MLI, Juárez AE, Locia EJ, Molina JT, Acosta HME

Language: Spanish
References: 0
Page: 67-83
PDF size: 1210.16 Kb.

ABSTRACT

Introduction: In the world, the use of extracts from plants to treat and prevent a great variety of diseases, has increased considerably. Among them, it stands out the use of the standardized extract obtained from dried leaves of Ginkgo biloba (EGb), a plant used for more than 2000 years as a phytotherapeutic remedy with recognized antioxidant properties for the treatment of neurological and cardiovascular diseases. Due to the high content of flavonoid glycosides, particularly quercetin and canferol, it has been used for the treatment of pathologies such as cancer. However, recent studies have shown that antioxidants can also have prooxidant activity, contributing to the progression of cancer and the development of tumors. Objective: Therefore, this work made an updated review of the use and applications of Ginkgo biloba, to have a clear idea of its pharmacological characteristics and its effects, both beneficial and adverse in in vivo and in vitro models.Material and Methods: An updated review was made in different sources of information on the effects and uses of Ginkgo biloba. Results and Conclusions: Although the evidence found indicates that the use of Ginkgo biloba extract is effective for the treatment of many diseases, it is necessary to know, in addition to its biological activity, warnings about adverse effects, toxicity, effective doses and administration times, among others, that allow the population to guarantee a good use of this product.