2006, Number S2
<< Back Next >>
Arch Cardiol Mex 2006; 76 (S2)
Acute coronary ischemic syndrome without st elevation. Role of glycoprotein IIb/IIIa inhibitors and percutaneous coronary interventions
Marco Antonio Peña DMA
Language: Spanish
References: 9
Page: 249-251
PDF size: 75.07 Kb.
ABSTRACT
Myocardial infarction without ST elevation and
unstable angina, represents a diagnostic challenge.
This Syndromes are caused by rupture of a
vulnerable plaque which determines intraluminal
thrombosis, distal embolism and coronary obstruction.
Administration of IIb/IIIa inhibitors produces
some benefits, mainly in those patients who are
taking to catheterization. Coronary intervention
based on a routine invasive strategy, has decreased
major cardiac events principally at long term.
REFERENCES
BRAUNWALD E, ANTMAN EM, BEASLEY JW, ET AL: ACC/AHA 2002 guideline update for the management of patients with unstable angina and non STsegment elevation myocardial infarction. J Am Coll Cardiol 2002; 40: 1366-74.
VAN DE WERF F, ARDISSINO D, BETRIU A, ET AL: Management of acute myocardial infarction in patients presenting with ST-segment elevation. The task force on the management of acute myocardial infarction of the European Society of Cardiology. Eur Heart J 2003; 24: 28-66.
FOX KA: Management of acute coronary syndromes: an update. Heart 2004; 90: 698-706.
LINDAHL B, TOSS H, SIEGBAHN A, ET AL: Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. N Engl J Med 2000; 343: 1139-1147.
TOPOL EJ, BYZOWA TV, PLOW EF: Platelet GPIIb/IIIa blockers. Lancet 1999; 353: 227-31.
ANTMAN EM: Glycoprotein IIb/IIIa inhibitors in patients with unstable angina/non-ST-segment elevation myocardial infarction: Appropriate interpretation of the guidelines. Am Heart J 2003; 146: S18-22.
ROFFI M, CHEW DP, MUKHERJEE D, ET AL: Platelet glycoprotein IIb/IIIa inhibition in acute coronary syndromes: gradient of benefit related to the revascularization strategy. Eur Heart J 2002; 23: 1441-1448.
ANTMAN EM, COHEN M, BERNINK PJ, MCCABE CH, ET AL: The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making. JAMA 2000; 284: 835-842.
METHA S, CANNON CP, FOX KA, WALLENTIN L, ET AL: Routine vs selective invasive strategies in patients with acute coronary syndromes. A collaborative meta-analysis of randomized trials. JAMA 2005; 293: 2908-2917.