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Colegio de Medicina Interna de México.

2018, Number 6

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Med Int Mex 2018; 34 (6)

Diagnostic approach of unknown primary tumor: fever of obscure origin of neoplasms

Rebolledo-García D, Contreras S, Granados-Moreno DL

Language: Spanish
References: 35
Page: 896-909
PDF size: 529.02 Kb.


ABSTRACT

The diagnosis of an unknown primary tumor is usually difficult due to its clinicalpathological behavior; its clinical manifestation is delayed so that the integration of a diagnostic protocol from a symptom or nonspecific clinical finding determines the delay of its approach. The characteristics of this tumor give it the minimum necessary tools to leave its niche of origin early, disseminating and staying distant from it, that is, an early metastasis. The development of molecular techniques that surpass the classic pathology has been an invaluable tool for its classification, having an absolute intention to separate those potentially sensitive to oncological treatment from those that are not. Without distinctive features that allow supposing it, before a seasoned clinician the initial suspicion of this entity is the best diagnostic tool.


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