Luciano SAC, Montejo VN, Loys FJL, Vila GE

Language: Spanish
References: 0
Page: 1-11
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ABSTRACT

Introduction: Breast cancer is the most frequent cancer and the main cause of death for cancer in women. It has a worse prognosis in young women due to more aggressive histology and higher recurrence rate.
Objective: To assess the results of the surgical treatment of breast cancer in women up to 40 years of age in Hermanos Ameijeiras Clinical-Surgical Hospital.
Method: A descriptive, longitudinal, retrospective and prospective study was carried out in the period from May 2005 to May 2015.
Results: 79 women aged up to 40 years with a diagnosis of breast cancer who underwent surgery were studied. It was found that 83.5 % were between 35 and 40 years old, with only 4 cases below 30 years (5.1 %). 38.4 % referred no family history of cancer. The most frequent clinical manifestations were the presence of nonpainful nodules in 93.7 % and nodule of hard consistency in 44.3 %. The tumors in stage I predominated, with 48.1 %, followed by other in stage II, with 32.9 %. The most widely used surgical technique was modified radical mastectomy, in 58 cases (73.4 %). In 37 patients (46.8 %), there was relapse of the disease. During the follow-up, 11 patients (13.9 %) deceased. The average time of overall survival was approximately 9 years, with a variation between 7 and 10 years. The mean time of disease-free survival was 5.5 years, with a variation between 5 and 6 years, which represents a 95 % confidence interval.
Conclusions: In women under 40 years of age, breast cancer has a worse prognosis due to a more aggressive histology and higher recurrence rate.