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ISSN 2683-1678 (Print)
Órgano Oficial de la Sociedad
Latinoamericana de lnfectología Pediátrica.
Órgano de la Asociación Mexicana de
Infectología Pediátrica, A.C.
Órgano difusor de la Sociedad Española
de lnfectología

2018, Number 2

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Rev Latin Infect Pediatr 2018; 31 (2)

Antimicrobial susceptibility of Enterococcus faecalis and faecium in a Third Level Hospital

Arredondo GJL, Echeguren FAM, Arzate BP, Medina CJH

Language: Spanish
References: 12
Page: 56-61
PDF size: 224.72 Kb.


ABSTRACT

This is a triple objective-based study rotating on description of the antimicrobial susceptibility of Enterococcus faecalis and Enterococcus faecium, the frequency of in-hospital infections caused by these microorganisms and vancomycin-resistant enterococci (VRE), and to check if there is any significant association between VRE-caused infections and diseases that compromised the immune response. The study is cross-sectional, retrospective and analytical using Enterococci positive cultures obtained from January to December, 2016, at the National Institute of Pediatrics (INP, for its Spanish acronym), Mexico. Antibiogram data were obtained while other data of interested were recompiled from the clinical files of the patients. There were 149 cultures in total, of which 68.5% were Enterococcus faecalis and 31.5% Enterococcus faecium. Enterococci isolated cultures occurred in 65.1% of the services and cultures associated with other microorganisms in 34.9%. Among the polymicrobial cultures, the strains of Pseudomonas aeruginose, Staphylococcus epidermidis, Escherichia coli and Klebsiella pneumoniae were found. Regarding antimicrobial resistant to ampicillin, penicillin and vancomycin, this was found to be very high for E. faecalis. The resistant to quinupristin and Dalfopristin is very high for the two strains. High level gentamycin resistance (HLGR) was identified in 28.9% of the cases while high level streptomycin resistance (HLSR) was found in 37.6% and vancomycin resistant enterococci (VRE) was only in 16.8%. The cultures that depicted two resistant mechanisms were 8.1% and with the three mechanisms of resistance in 1.3%. The association between vancomycin resistant enterococci and the presence of comorbidities showed significant statistical difference in the cases with immunological, neurological, metabolical and renal alterations. The study showed that epidemiological surveillance is extremely essential as well as informing medical and non-medical personnel of the paramount need to use in-hospital infection control measures.


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