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2018, Number 4

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Rev Med MD 2018; 9.10 (4)

Obesity and infections

Preciado-Ortiz ME, Sánchez-Reyes K, Álvarez-Zavala M, González-Hernández LA, Ramos-Solano M, Andrade-Villanueva J

Language: Spanish
References: 23
Page: 341-344
PDF size: 543.59 Kb.


ABSTRACT

Obesity is a public health problem. The interaction between obesity and the development of several chronic diseases is well stablished; however, its relation with the development of infectious diseases is not entirely clear. There is a close association between molecules produced by adipocytes (i.e. adipokines), with metabolic regulation and the immune response, nevertheless, this interaction is altered in obesity, inducing a metabolic imbalance and an immunocompromised state. Obesity has been associated with an increment in susceptibility and severity of infections, especially those of respiratory tract, skin and post-surgical infections, these infections increase the hospital stay and the risk of death in obese individuals. Nonetheless, more studies are necessary to understand the mechanisms that induce this relationship.


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