2018, Number 4
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Rev Invest Clin 2018; 70 (4)
Borrelia Infection in Latin America
Robles A, Fong J, Cervantes J
Language: English
References: 70
Page: 158-163
PDF size: 179.25 Kb.
ABSTRACT
Lyme disease (LD) is a multisystemic inflammatory disease caused by pathogenic spirochetes, belonging to the genospecies
complex
Borrelia burgdorferi sensu lato (B.b.s.l.). Around the world, distinct species of
Ixodes tick vectors transmit different
species of
Borrelia. Despite the rising recognition and occurrence of tick-borne disease in Latin America, serology has proven
to be inconclusive in detecting suspected LD cases. Recently, new B.b.s.l. strains or new related species have been described in
Brazil, Uruguay, and Chile. This could explain the lack of confirmatory tests, such as indeterminate Western blots (WBs) and
polymerase chain reactions, in detecting suspected LD cases in this region of the world. Future studies will need to determine
the extension of novel B.b.s.l. species infections in ticks, reservoirs, and humans in Latin America. The existence of these new
Borrelia genomic species should prompt the development of innovative diagnostic and clinical approaches.
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