González EC, Rodríguez MN

Language: Spanish
References: 0
Page: 81-89
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ABSTRACT

Introduction: prostate cancer is the most frequent in the male population and the second cause of death in older than 50 year-old men. About the 23 % of these patients present bone metastases in the moment of the diagnosis.
Objective: to determine the appearance of bone metastasis by gammagraphy in patients with prostate cancer and its relation between the levels of specific prostatic antigen, the results of the bone gammagraphy and Gleason points.
Method: an observational, descriptive, transverse study was carried out in patients with diagnosis of prostate cancer in CIMEQ in the period from January, 2013 to December, 2016. Patients who received previous treatment for prostatic diseases were excluded. Demographic variables, bone gammagraphy, levels of specific prostatic antigen and histological results according to Gleason and main symptoms were analyzed.
Results: the average age was 71,45 years old and the prevailing skin color was white. Bone gammagraphy showed bone metastases in 55 patients, they increased proportionally with the levels of specific prostatic antigen, and Gleason. The gammagraphy pattern that prevailed was the multiple lesion with an average level of specific prostatic antigen of 66,70 ng/ml.
Conclusions: more than 50% of the sample presented bone metastatic lesions. The values of specific prostatic antigen were higher than 20 ng/ml, which can suggest the presence of metastasis. Patients with biopsy of prostate with Gleason of low differentiation level have higher risk of suffering from bone metastases.