Ramos CÁE, Blanco BSL, Rodríguez CM, Sánchez PY, Sánchez NR

Language: Spanish
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ABSTRACT

Introduction: The incidence of infections associated with Clostridium difficile (IACD), in the global context, including Cuba, varies between 0.6 and 2.1% of the total number of hospitalized patients.
Objective: To characterize clinical and epidemiologically patients with post-mortem diagnosis of pseudomembranous colitis.
Material and Methods: An observational, descriptive, cross-sectional study was conducted, using a universe of 49 patients who died at the "Abel Santamaría Cuadrado" Hospital, who were diagnosed with pseudomembranous colitis through necropsy. The variables studied were: sex, length of stay, service of origin, antibiotic prescription, use of nutrition through a nasogastric tube and the use of Omeprazole.
Results: The average age was 73.2 years and those who were 65 or older predominated. The average stay was 38 days and more than 70% came from intensive care units. In 63.2%, PPI was used in the treatment and 71.4% needed food through SNG. The most commonly used antibiotic groups were the 3rd generation cephalosporin, followed by the quinolones, the 4th generation cephalosporin and the carbapenems.
Conclusions: The clinical and epidemiological characteristics of patients diagnosed with infections associated with Clostridium difficile generally correspond to elderly patients, with long hospital stay, recent use of antibiotics, stay in intensive care units, with feeding through SNG and treatment with PPI.