Ávalos SR, Solano MHA, García PV, González EE, Sánchez VG, Domínguez VG, Ruvalcaba NHG

Language: Spanish
References: 26
Page: 10-17
PDF size: 83.68 Kb.

ABSTRACT

Introduction: Urothelial cancer of superior tract that surround renal pelvis and ureter are rare, only represent 5% of all urothelial tumors and 7% of all renal tumors. In Mexico do not exist reports about the prevalence of superior tract urothelial tumors. Numerous factors contribute to the development of urothelial tumors of superior urinary tract: Age, sex, race and the most important factor is nicotinism. Other implied factors are coffee, ciclofosfamide, exposition to professional carcinogen, antecedent of infections and lithiasis of urinary tract, use of Chinese grass to lose weight and hereditary tendencies. The presentation sign or symptom more frequent is hematuria. The gold standard for treatment is total nephreureterectomy with excision of a ipsilateral bladder mucosae cuff. Methods: A cross-sectional descriptive noncomparative study is made in Hospital de Especialidades del Centro Médico Nacional de Occidente of Instituto Mexicano del Seguro Social, from 1st of January 1985 to 31 of December 2004. Results: 21 cases were included. Masculine sex predominated, age average was of 59.6 years, the more important risk factor was nicotinism. Hematuria was the most important manifestation. 95% were located in renal pelvis. Predominant histological variant was the transitional. Treatment consisted of radical nephreureterectomy. Free disease period was considered 35 months in average. Conclusions: Superior urinary tract affection is infrequent in Mexico. The presented casuistry has great similarities with the published ones at international level.

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