Carrillo-Esper R, Peñaherrera-Oviedo CA, Tamariz-Amador LE

Language: Spanish
References: 25
Page: 128-136
PDF size: 182.99 Kb.

ABSTRACT

Neuroendocrine dysfunction is a complication of acute brain injury characterized by disruption of the hypothalamic-pituitary axis, due to direct damage of vascular origin. The disease characterizes by alterations of one or many of the hormonal systems regulated by the pituitary gland, sometimes even reaching frank hypopituitarism. One of the most important causes is subarachnoid hemorrhage. The hormonal deficit appears shortly after the occurrence of the bleeding and may remain long term, which causes symptoms that are secondary to low levels of certain hormones and some neuropsychological disorders that greatly affect life quality of those patients, whose prognosis was already functionally altered by the hemorrhage itself. Hormone replacement therapy is indicated both in the acute phase and in case of permanent deficiency of each hormone. We provide an update on this subject, in order to better understand the disease, when to suspect it, how to identify it, and suggest an appropriate management.

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