Rodríguez ML, Sarduy NMR, Baladrón CI, Solares AAM, Martínez CYM

Language: Spanish
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ABSTRACT

Introduction: Cervical intraepithelial lesions are signs of cervical cancer, a disease that caused 465 deaths in Cuba in 2015.
Objective: To describe the evolution of low-grade intraepithelial lesions of the cervix during a biennium according to the provisions of the National Program of Early Diagnosis of Cervical Cancer.
Methods: A descriptive, longitudinal and prospective study was carried out on 79 patients diagnosed by cytology with a low-grade squamous intraepithelial lesion from September 1, 2012 to August 31, 2013 at "Ramón González Coro" Gyneco- -Obstetric Hospital. These subjects received an evolutionary follow-up every six months for two years.
Results: 54.4 % were between 25 and 39 years of age; 65.8 % had negative cytology between 6 and 18 months. In the two years of evolution, 25.3 % of the total progressed to a high-grade lesion. There was good cytocolposcopic correlation in 80 % of the patients. The calculation of the median of the atypical transformation zone in the high-grade lesions was 25 %, much higher than the low-grade ones. There was histological confirmation in all cases whose lesion progressed.
Conclusions: Negative cytology in our patients was assessed during the 18 months of follow-up period. There was good cytohistological relationship, but not so for colpohistological relationship. The evolution was not related to the sociodemographic variables except with the use of IUD. Lesions that occupy more than 20 % of the transformation zone were associated with progression towards a high-grade squamous intraepithelial lesion.