2018, Number 2
<< Back Next >>
Rev Clin Esc Med 2018; 8 (2)
Diagnóstico y Manejo de la Primera Convulsión
Sequeira QCM, Chang SJ
Language: Spanish
References: 27
Page: 11-21
PDF size: 417.66 Kb.
ABSTRACT
A seizure is defined as excesive and
hypersynchronic electric brain activity that
generates transitory neurologic symptoms, which
must be differentiated among a wide range of
potential neurologic and non-neurologic
diagnosis. Seizures must be classified as focal or
generalized, acute symptomatic or remote
symptomatic and provoked and unprovoked. Not
all patients that have a seizure will do so again.
Every patient with a convulsive episode must
receive an electroencephalogram and a magnetic
resonance. The risk of recurrence after a first
unprovoked seizure is 36% during the first year
and 45% during the second year. Those who
present with cortical abnormalities in image
studies and epileptic activity in
electroencephalogram will elevate this risk up to
60%. Treatment with antiepileptic drugs must be
initiated in those patients that fulfill criteria for
epilepsy and discussed in those with a single
unprovoked seizure. After 2 years free of crisis
discontinuation of drug therapy can be
considered.
REFERENCES
Brumholz K, Wiebe S, Gronseth G et al. Evidence-Based Guideline: Management of an Unprovoked First seizure in adults. Epilepsy Currents 2015; 15(3): 144–152.
Krumholz A, Wiebe S, Gronseth G et al. Practice Parameter: Evaluating an apparent unprovoked first seizure in adults (an evidencebased review). Neurology 2007; 69(21): 1996- 2007.
Bergey G. Management of a First Seizure. Continuum (Minneap Minn) 2016;22(1):38–50.
Louis E, Cascino G. Diagnosis of Epilepsy and Related Episodic Disorders. Continuum (Minneap Minn) 2016;22(1):15–37.
Scheffer I, Berkovic S, Capovilla G. ILAE classification of the epilepsies: Position paper of the ILAE Comission for the Classification and Terminology. Epilepsia 2017; 58(4):512–521.
Daroff R, Jankovic J, Mazziotta J et al. Bradley’s Neurology in Clinical Practice. Sev- enth Edition. Chapter 101: Epilepsies. Elsevier. 2016; 1563-1614.
Hauser W, Beghi E. First seizure definitions and worldwide incidence and mortality. Epilepsia 2008; 49(Suppl. 1): 8–12.
Hauser L, Stephenson A. Harrison’s Neurology in Clinical Medicine. 4th Edition. Chapter 31: Seizures and Epilepsy. McGrawHill Education. 2017;297-322.
Fisher RS, Acevedo C, Arzimanoglou A, et al. ILAE official report: a practical clinical definition of epilepsy. Epilepsia 2014;55(4): 475- 482.
Majersik J. Inherited and Uncommon Causes of Stroke. Continuum (Minneap Minn) 2017;23(1):211–237.
Manji H, Connolly S, Kitchen N Et al. Manual Oxford de Neurología. Segunda edición. Capítulo 3: Urgencias Neurológicas. Aula Médica. 2016; 78-79.
Biller J. Neurología Práctica. Cuarta Edición. Capítulo 6: Enfoque del paciente con convulsiones. Wolters Kluvers. 2011; 51-60.
Shibasaki H, Hallett M. The Neurologic Examination Scientific Basis for Clinical Diagnosis. Chapter 24: Paroxysmal and Functional Disorders. Oxford University Press. 2016; 237.
ILAE. Epilepsy Imitators. 2017. Obtenido de: https://www.epilepsydiagnosis.org/epilepsyimitators. html
Chen D, LaFrance C. Diagnosis and Treatment of Nonepileptic Seizures. Continuum (Minneap Minn) 2016; 22(1):116–131.
Kuehn B. New Adult First Seizure Guideline Emphasizes an Individualized Approach. JAMA 2015; 314(2): 111-113.
Samuels M, Rooper A. Samuels’s Manual of Neurologic Therapeutics. Ninth Edition. Chapter 2: Epilepsy. Wolters Kluwer, 2017; 37- 76.
Maganti RK and Rutecki P. EEG and epilepsy monitoring. Continuum (Minneap Minn). 2013; 19:598-622.
Smith SJ. EEG in the diagnosis, classification, and management of patients with epilepsy. Journal of neurology, neurosurgery, and psychiatry. 2005; 76(2):2-7.
Siegler J. First Seizure of Life. 2017. Obtenido de: http://brainwaves.me/first-seizureof- life/.
Sofat P, Teter B, Kavak K et al. Time interval providing highest yield for initial EEG in patients with new onset seizures. Epilepsy Research. 2016; 229–232
Hauser WA, Rich SS, Lee JR et al. Risk of recurrent seizures after two unprovoked seizures. N Engl J Med 1998;338(7): 429-434.
Bora I, Seckin B, Zarifoglu M et al. Risk of recurrence after first unprovoked tonicclonic seizure in adults. J Neurol 1995;242: 157– 163.
Kho K, Lawn D, Dunne W. First seizure presentation. Do multiple seizures within 24 hours predict recurrence? Neurology 2006; 67: 1047–1049.
No authors listed. Randomized clinical trial on the efficacy of antiepileptic drugs in reducing the risk of relapse after a first unprovoked tonic-clonic seizure. First Seizure TrialGroup (FIR.S.T. Group). Neurology 1993; 43(3 pt 1):478-483.
Marson A, Jacoby A, Johnson A et al. Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizures: a randomised controlled trial. Lancet 2005; 365(9476):2007-2013.
Britton J. Antiepileptic drug therapy: when to start, when to stop. Continuum Lifelong Learning Neurol 2010; 16(3):105–120.