Valladares GJC, Gallardo GLA, Salado BJC, Espinosa AL

Language: Spanish
References: 15
Page: 138-141
PDF size: 165.21 Kb.

ABSTRACT

Trichosporonosis is a rare, invasive, opportunistic infection with a mortality rate ranging from 50 to 80%. It has often been found in patients with hematologic neoplasms, such as in the patient whose case is described. The main clinical features are fever and fungemia. We describe the case of a 56-year-old woman with acute biphenotypic leukemia who developed neutropenic fever after initiating chemotherapy. After diagnostic tests were performed, Trichosporon asahii was identified from a catheter tip culture. After removal of the catheter, remission of the fever and a reduction in inflammatory markers was achieved. This case represents a probable infection by Trichosporon, since it occurred in a patient with neutropenic fever and the organism was identified from a catheter tip culture. The mainstay of treatment are azoles; the antifungal used in this case was voriconazole. Three months after the diagnosis, the patient underwent allogeneic bone marrow transplant and subsequently developed neutropenic colitis, Clostridium difficile infection and septic shock, culminating with the patient’s death. This article describes an infection by Trichosporon asahii in a patient with neutropenic fever. Additionally, we provide a concise review of the disease’s features, diagnostic criteria, and management.

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