2001, Number 1
Comparative study of the pursuit with iodine 131 and technetium
Language: Spanish
References: 16
Page: 12-15
PDF size: 44.02 Kb.
ABSTRACT
Patients with differentiated thyroid cancer after initial treatment require a pursuit for life. In the pursuit of patient with differentiated thyroid cancer is suitable the realization of either rake with iodine 131 or with technetium 99–sestamibi. The objective of the present study is to know which radiopharmaceutical has bigger certainty in the detection of tissue remainder and/or metastatic. Twenty-six patients were selected with differentiated thyroid cancer, to the same patient they were made rake, with technetium 99-sestamibi and with Iodine 131; the results of the two studies and the statystical analysis were compared it was carried out by means of the test of Chi square. Nine patients were positive for iodine 131 (34%) and 5 (19%) positive for technetium 99-sestamibi, obtaining a significant p (p ‹ 0.05). The sensibility reported for the iodine 131 was of 70%, with a specificity of 19%; the sensibility obtained for the technetium 99-sestamibi is approximately of 19%. In our study to be better the iodine 131 that the technetium 99-sestamibi in the detection of fabric residual and/or metastatic. The biggest advantage in the technetium 99-sestamibi is its application without necessity of suspending the treatment with hormonal, but on the other hand the biggest disadvantage is its low sensibility in differentiated carcinoma.REFERENCES
Ladenson PW, Braverman LE, Mazzaferri EL, Davis FB, Cooper DS, Garber JR, Wondisford FE, Davies TF, Degroot LJ, Daniels GH, Ross DS, Weintraub BD. Comparison of administration of recombinant human thyrotropin with and withdrawal of thyroid hormone for radioactive iodine scanning in patients with thyroid carcinoma. N Engl J Med 1997; 337: 888-95.
Dadparvar S, Chevres A, Tulchilsky M, Badrinath LK, Khan AS, Slizofski WJ. Clinical utility of technetium-99m methoxisobutylisonitrile imaging in differentiated thyroid carcinoma: comparison with thalium-201 and iodine-131 Na scintigraphy, and serum thyroglobulin quantitation. Eur J Nucl Med 1995; 22: 1330-38.