2018, Number 1
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Rev Invest Clin 2018; 70 (1)
Chewing Xylitol Gum could Accelerate Bowel motility Recovery after Elective Open Proctectomy for Rectal Cancer
Yang P, Long WJ, Li W
Language: English
References: 26
Page: 53-58
PDF size: 85.03 Kb.
ABSTRACT
Background: A number of studies with conflicting results have evaluated the effect of chewing gum on post-operative
gastrointestinal recovery in patients after major colorectal surgery.
Objective: The objective of the study was to study the efficacy
of chewing gum in patients with rectal cancer after elective open proctectomy only.
Methods: A randomized controlled clinical
trial was performed. We recruited patients who would undergo elective open proctectomy for rectal cancer in Sichuan Academy
of Medical Sciences and Sichuan Provincial People’s Hospital. Patients in the intervention arm received chewing gum 3 times a day
postoperatively. All patients in the trial were placed on the same perioperative management and standardized post-operative care
plans. The primary outcome was time to the first peristalsis sounds, time to first flatus and the first defecation.
Results: A total
of 89 patients were recruited. The time to the first flatus was 42.33 ± 3.46 h in the gum group and 49.20 ± 1.42 h in the control
group (p ‹ 0.05). The time to the first defecation was significantly shorter in the gum-chewing group than in the control group
(66.07 ± 2.36 vs. 78.37 ± 1.62 h; p ‹ 0.05). Post-operative ileus (POI) was confirmed in 2 patients in the gum-chewing group and
in 7 in the control group (7.0% vs. 23.9%; p = 0.028).
Discussion: The present study suggests that chewing gum is a method to
reduce the time to first flatus, time to first defecation and POI in patients undergoing elective open proctectomy for rectal cancer.
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