Cabrera RBA, García GMB, López PR, Ramos RY, Triana PI, Álvarez LY

Language: Spanish
References: 0
Page: 36-44
PDF size: 453.68 Kb.

ABSTRACT

Introduction: morphometric procedures are very useful to diagnose malignant neoplasms as they complement other qualitative methods used.
Objective: a descriptive cross-sectional study of renal cell carcinoma was carried out to characterize morphometrically renal tubule epithelial cell nuclei in the different histological types of this disease.
Methods: 30 biopsies of patients diagnosed at “Arnaldo Milián Castro” Clinico-Surgical Provincial Hospital from Villa Clara were studied between January, 2012 and December, 2013. Measurements made through the ImageJ computer program allowed us to determine the value of variables.
Results: chromophobe carcinoma had the highest average values among the studied variables, except for nuclear circularity which was higher in cell carcinoma. Correlational study determined significant, strong and positive relations among the majority of the variables, while nuclear circularity was significant, moderate and negative in most of them, with the exception of larger diameter which was non-significant.
Conclusions: there was variability in the morphometric parameters studied and correlation among most of the variables in the different histological types of renal cell carcinoma, with the exception of nuclear circularity.