2005, Number 3
Psychophysical tests and confocal scanning laser tomography in subjects with suspicious excavation.
Ramírez GL, Hartleben MC, Casab RH, Korder OV
Language: Spanish
References: 0
Page: 145-154
PDF size: 439.64 Kb.
ABSTRACT
Objective: The aim of this study was to find out how blue-on-yellow perimetry and frequency-doubling perimetry results correlate with structural measures obtained with confocal scanning laser tomography for the diagnosis of early glaucoma in subjects with clinically abnormal excavation.Material and methods: The study population consisted of 19 normal subjects, 34 patients with clinically abnormal excavation and 15 patients with early glaucoma. All the patients were examined with Heidelberg retina tomography, Humphrey perimeter, program 24-2 white-on-white (WW), blue-on-yellow perimetry (BY) and frequency-doubling perimetry (FDT). A Multiple regression linear analysis was applied with the purpose of establishing the strength of the association between functional and structural variables.
Results: It was found that in the group of suspicious patients the most important predictors were the RNFL cross-section area and Mean RNFL thickness which significantly correlated with B-Y visual field MD. It was found that when applying a discrimination function analysis with these parameters to classify the patients of the group II, an agreement of 61.2% existed with the results of HRT.
Conclusion: The ACP-CFNR, PE-CFNR and the media deviation of the yellow-white campimetry are tests with discriminative power for the classification of patients with suspect of glaucoma. It is necessary to carry out a longitudinal study to elaborate a classification system for patients with incipient glaucoma.