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Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio

2018, Number 1

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Rev Mex Patol Clin Med Lab 2018; 65 (1)

Usefulness of myeloculture for the etiological diagnosis of bacterial infections

Oliver SAC, Bove BV, Bradvica VV, Batista UN, Palacio PR, Guillermo EC, Díaz FL, Seija SV

Language: Spanish
References: 17
Page: 34-38
PDF size: 237.24 Kb.


ABSTRACT

Introduction: Bone marrow culture is part of the diagnostic algorithm of infectious processes in patients with fever of unknown origin (FUO) in our country. However, there are controversies regarding its usefulness on an international level. The primary objective of the study was to evaluate the ability of bone marrow cultures to recover specific and nonspecific bacterial agents in patients with FUO and/or cytopenias assisted in the Hospital de Clinicas. Material and methods: A retrospective study that included patients who underwent marrow culture at the Hospital de Clinicas between March 2007 and December 2013. Results: 69 patients were included: 44 because of cytopenia and 25 because of FUO. 58 were HIV positive. Three of the 69 marrow cultures were positive for non-specific bacteria; in one case, methicillin-resistant Staphylococcus aureus was isolated, and in two, Staphylococcus epidermidis. Marrow culture was performed for specific germs in 59 patients; three were positive, all of them in HIV positive patients; two for Mycobacterium avium complex (MAC), both studied due to cytopenias, and one for Mycobacterium tuberculosis (MT), requested for FUO. One of the 69 marrow cultures performed determined changes in therapeutics. Conclusions: Bone marrow culture had a low rate of recovery of an infectious agent with respect to the total of studies performed. Being an invasive study with slow results, in the light of studies with greater potential, we propose its current low usefulness in our population.


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