Gaeta MM

Language: Spanish
References: 19
Page: 17-21
PDF size: 137.93 Kb.

ABSTRACT

The Juvenile Nasoangiofibroma (JNA), also known as Nasopharyngeal Angiofibroma, juvenile fibroma, angiofibroma or nasopharyngeal hemangioma, it´s the most frequent benign tumor originated on the nasopharynx, it constitutes less than the 0.05% of all tumors of head and neck reported into the available medical literature. Its incidence practically aims to him at being exclusive of men in ages next to the puberty. In relation to their etiology multiple causes have been suggested; however, no one has been accepted. Around the world many cases are reported, despite this, only a few authors publish big samples. This represents, in the theoretical scope, a problem at the time of trying to make an analysis of its real incidence. Basing us in the available data, we can affi rm that it appears with more frequency in Asian countries that in their European or African homologous; however, in America, particularly in Mexico, it has been described with particular frequency. The supposed "inherited" susceptibility of the old settlers of America (amerindians) from their remote Asian ancestors that, in theory, migrated from Asia and crossed the Bering Strait to settle in our continent 30,000 years ago. The greater frequency of this pathology appears in individuals with O and Rh positive blood types, considering this like a racial marker.
MATERIALS AND METHODS
28 Clinical files with diagnosis of JNA were analyzed, corroborated by histopathology.
RESULTS
All the patients were male between 10 and 20 years old, all original of Mexico and 92% of such had O Rh positive blood type.
CONCLUSION
The Juvenile Nasoangiofibroma is very frequent in America, particularly in Mexico; most of the patients exhibit O Rh positive blood type. All the affected patients are men with ages around the puberty.

REFERENCES

1. 1.- Economou TS, Abemayor EA, Ward PH. Juvenile Nasopharyngeal Angiofibroma: An update of the UCLA experience, 1960-1985. Laryngoscope 1988;98:170-175

2. 2.-Waldman SR, et al. Surgical Experience with Nasopharyngeal Angiofibroma. Arch Otolaryngol 1981;107:677-682

3. 3.-Siniluoto TM, et al. Value of preoperative embolization in surgery for Nasopharyngeal Angiofibroma. J Laryngol Otol 1993;107:514-521

4. 4.-Hernández RV, Avila SE, Avila E. Angiofibroma Juvenil Nasofaríngeo. Tratamiento multidisciplinario. Servicio de Oncología, Hospital central Militar de México, 1981.

5. 5.-Harrison DF. The natural history, pathogenesis and treatment of Juvenile Angiofibroma . Arch Otolaryngol Head Neck Surg 1987;113:936-942

6. 6.-Guertl B, et al. Nasopharyngeal Angiofibroma: An APC-Gene associated tumor?. Hum Pathol 2000;31:1411-1413

7. 7.-Schiff M, et al. Juvenile Nasopharyngeal Angio-fibroma contain an angiogenic growth factor: Basic FGF. Laryngoscope 1992:940-945.

8. 8.-Gullane PJ, et al. Juvenile Angiofibroma: A review of the literature and a case series report. Laryngoscope 1992; 102:928-933

9. 9.-Chandler JE, et al. Nasopharyngeal Angiofibroma: Staging and management. Ann Otol Rhinol Laryngol 1984;93:322-329

10. 10.-Antonelli AR, Carpiello J, Di Lorenzo D. Diagnosis, staging, and treatment of Juvenile Nasopharyngeal Angiofibroma. Laryngoscope 1987;97:1319-1325.

11. 11.-Shikani AH, Richtsmeier WJ. Juvenile Nasopharyngeal Angio-fibroma tumor models. Failure of androgens to stimulate growth in nude mice and vitro. Arch Otolaryngol Head Neck Surg 1992;118:256-259

12. 12.-Bross D, et al. Tumores nasales. Experiencia de diez años del departamento de Otorrinolaringología del hospital “Dr. Manuel Gea Gonzalez”, An ORL Mex 1996;41:208-212

13. 13.-Arrieta JR, et al. Cirugía endoscópica en Angiofi-broma Juvenil. Experiencia en nueve pacientes. An ORL Mex 1997;42:78-83.

14. 14.- Jones GC, et al. Juvenile Angiofibromas. Arch Otolaryngol Head Neck Surg 1986;41:208-212

15. 15.- Fitzpatrick PJ, Briant DR, Berman JM. The Nasopharyngeal Angiofibroma. Arch Otolaryngol 1980;106:234-236

16. 16.-Quito JW, et al. Cirugía de Angiofibroma Nasofaríngeo Juvenil. An ORLMex1999;44:90-94

17. 17.-Biller HF. Juvenile Nasopharyngeal Angiofibroma. Ann Otol Rhinol laryngol 1978;87:630-632.

18. 18.-Tandon DA, et al. Nasopharyngeal Angiofibroma (A nine year experience). J Laryngol Otol 1988;102:805-809

19. 19.-Chih-Wen Twu, Chen-Yi Hsu, Rong-San Jiang. Surgical treatment of Nasopharyngeal Angiofi-broma. Mid Taiwan J 2002;7:71-75 .